TopFIND 4.0

P48540: Glial cell line-derived neurotrophic factor

General Information

Protein names
- Glial cell line-derived neurotrophic factor
- mGDNF
- Astrocyte-derived trophic factor
- ATF
Gene names Gdnf
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P48540

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKLWDVVAVC LVLLHTASAF PLPAGKRLLE APAEDHSLGH RRVPFALTSD SNMPEDYPDQ 
        70         80         90        100        110        120 
FDDVMDFIQA TIKRLKRSPD KQAAALPRRE RNRQAAAASP ENSRGKGRRG QRGKNRGCVL 
       130        140        150        160        170        180 
TAIHLNVTDL GLGYETKEEL IFRYCSGSCE SAETMYDKIL KNLSRSRRLT SDKVGQACCR 
       190        200        210    
PVAFDDDLSF LDDNLVYHIL RKHSAKRCGC I

Isoforms

- Isoform 2 of Glial cell line-derived neurotrophic factor - Isoform 3 of Glial cell line-derived neurotrophic factor

Sequence View

        10         20         30         40         50         60 
MKLWDVVAVC LVLLHTASAF PLPAGKRLLE APAEDHSLGH RRVPFALTSD SNMPEDYPDQ 
        70         80         90        100        110        120 
FDDVMDFIQA TIKRLKRSPD KQAAALPRRE RNRQAAAASP ENSRGKGRRG QRGKNRGCVL 
       130        140        150        160        170        180 
TAIHLNVTDL GLGYETKEEL IFRYCSGSCE SAETMYDKIL KNLSRSRRLT SDKVGQACCR 
       190        200        210    
PVAFDDDLSF LDDNLVYHIL RKHSAKRCGC I         10         20         30         40         50         60 
MKLWDVVAVC LVLLHTASAF PLPAGKRLLE APAEDHSLGH RRVPFALTSD SNMPEDYPDQ 
        70         80         90        100        110        120 
FDDVMDFIQA TIKRLKRSPD KQAAALPRRE RNRQAAAASP ENSRGKGRRG QRGKNRGCVL 
       130        140        150        160        170        180 
TAIHLNVTDL GLGYETKEEL IFRYCSGSCE SAETMYDKIL KNLSRSRRLT SDKVGQACCR 
       190        200        210    
PVAFDDDLSF LDDNLVYHIL RKHSAKRCGC I



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Evidence Codes:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)