P48542: G protein-activated inward rectifier potassium channel 2

General Information

Protein names	- G protein-activated inward rectifier potassium channel 2 - GIRK-2 - Inward rectifier K(+) channel Kir3.2 - Potassium channel, inwardly rectifying subfamily J member 6
Gene names	Kcnj6
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P48542

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform GIRK2-1 of G protein-activated inward rectifier potassium channel 2 - Isoform GIRK2B of G protein-activated inward rectifier potassium channel 2 - Isoform GIRK2C of G protein-activated inward rectifier potassium channel 2

Sequence View

        10         20         30         40         50         60
MTMAKLTESM TNVLEGDSMD QDVESPVAIH QPKLPKQARD DLPRHISRDR TKRKIQRYVR
        70         80         90        100        110        120
KDGKCNVHHG NVRETYRYLT DIFTTLVDLK WRFNLLIFVM VYTVTWLFFG MIWWLIAYIR
       130        140        150        160        170        180
GDMDHIEDPS WTPCVTNLNG FVSAFLFSIE TETTIGYGYR VITDKCPEGI ILLLIQSVLG
       190        200        210        220        230        240
SIVNAFMVGC MFVKISQPKK RAETLVFSTH AVISMRDGKL CLMFRVGDLR NSHIVEASIR
       250        260        270        280        290        300
AKLIKSKQTS EGEFIPLNQS DINVGYYTGD DRLFLVSPLI ISHEINQQSP FWEISKAQLP
       310        320        330        340        350        360
KEELEIVVIL EGIVEATGMT CQARSSYITS EILWGYRFTP VLTMEDGFYE VDYNSFHETY
       370        380        390        400        410        420
ETSTPSLSAK ELAELANRAE VPLSWSVSSK LNQHAELETE EEEKNPEELT ERNGDVANLE

NESKV         10         20         30         40         50         60
MTMAKLTESM TNVLEGDSMD QDVESPVAIH QPKLPKQARD DLPRHISRDR TKRKIQRYVR
        70         80         90        100        110        120
KDGKCNVHHG NVRETYRYLT DIFTTLVDLK WRFNLLIFVM VYTVTWLFFG MIWWLIAYIR
       130        140        150        160        170        180
GDMDHIEDPS WTPCVTNLNG FVSAFLFSIE TETTIGYGYR VITDKCPEGI ILLLIQSVLG
       190        200        210        220        230        240
SIVNAFMVGC MFVKISQPKK RAETLVFSTH AVISMRDGKL CLMFRVGDLR NSHIVEASIR
       250        260        270        280        290        300
AKLIKSKQTS EGEFIPLNQS DINVGYYTGD DRLFLVSPLI ISHEINQQSP FWEISKAQLP
       310        320        330        340        350        360
KEELEIVVIL EGIVEATGMT CQARSSYITS EILWGYRFTP VLTMEDGFYE VDYNSFHETY
       370        380        390        400        410        420
ETSTPSLSAK ELAELANRAE VPLSWSVSSK LNQHAELETE EEEKNPEELT ERNGDVANLE

NESKV         10         20         30         40         50         60
MTMAKLTESM TNVLEGDSMD QDVESPVAIH QPKLPKQARD DLPRHISRDR TKRKIQRYVR
        70         80         90        100        110        120
KDGKCNVHHG NVRETYRYLT DIFTTLVDLK WRFNLLIFVM VYTVTWLFFG MIWWLIAYIR
       130        140        150        160        170        180
GDMDHIEDPS WTPCVTNLNG FVSAFLFSIE TETTIGYGYR VITDKCPEGI ILLLIQSVLG
       190        200        210        220        230        240
SIVNAFMVGC MFVKISQPKK RAETLVFSTH AVISMRDGKL CLMFRVGDLR NSHIVEASIR
       250        260        270        280        290        300
AKLIKSKQTS EGEFIPLNQS DINVGYYTGD DRLFLVSPLI ISHEINQQSP FWEISKAQLP
       310        320        330        340        350        360
KEELEIVVIL EGIVEATGMT CQARSSYITS EILWGYRFTP VLTMEDGFYE VDYNSFHETY
       370        380        390        400        410        420
ETSTPSLSAK ELAELANRAE VPLSWSVSSK LNQHAELETE EEEKNPEELT ERNGDVANLE

NESKV

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P48542-1-unknown	MTMAKL...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P48542-1-unknown	MTMAKL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78768
P48542-1-unknown	MTMAKL...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78769
P48542-19-unknown	MDQDVE...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt78770
P48542-19-unknown	MDQDVE...	19	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000130321
P48542-19-unknown	MDQDVE...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105829
P48542-19-unknown	MDQDVE...	19	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt105830

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...TERNGD	414	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74386
...TERNGD	414	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000093558
...NESKV	425	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)