TopFIND 4.0

P48549: G protein-activated inward rectifier potassium channel 1

General Information

Protein names
- G protein-activated inward rectifier potassium channel 1
- GIRK-1
- Inward rectifier K(+) channel Kir3.1
- Potassium channel, inwardly rectifying subfamily J member 3
Gene names KCNJ3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P48549

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSALRRKFGD DYQVVTTSSS GSGLQPQGPG QDPQQQLVPK KKRQRFVDKN GRCNVQHGNL 
        70         80         90        100        110        120 
GSETSRYLSD LFTTLVDLKW RWNLFIFILT YTVAWLFMAS MWWVIAYTRG DLNKAHVGNY 
       130        140        150        160        170        180 
TPCVANVYNF PSAFLFFIET EATIGYGYRY ITDKCPEGII LFLFQSILGS IVDAFLIGCM 
       190        200        210        220        230        240 
FIKMSQPKKR AETLMFSEHA VISMRDGKLT LMFRVGNLRN SHMVSAQIRC KLLKSRQTPE 
       250        260        270        280        290        300 
GEFLPLDQLE LDVGFSTGAD QLFLVSPLTI CHVIDAKSPF YDLSQRSMQT EQFEIVVILE 
       310        320        330        340        350        360 
GIVETTGMTC QARTSYTEDE VLWGHRFFPV ISLEEGFFKV DYSQFHATFE VPTPPYSVKE 
       370        380        390        400        410        420 
QEEMLLMSSP LIAPAITNSK ERHNSVECLD GLDDITTKLP SKLQKITGRE DFPKKLLRMS 
       430        440        450        460        470        480 
STTSEKAYSL GDLPMKLQRI SSVPGNSEEK LVSKTTKMLS DPMSQSVADL PPKLQKMAGG 
       490        500    
AARMEGNLPA KLRKMNSDRF T

Isoforms

- Isoform 2 of G protein-activated inward rectifier potassium channel 1

Sequence View

        10         20         30         40         50         60 
MSALRRKFGD DYQVVTTSSS GSGLQPQGPG QDPQQQLVPK KKRQRFVDKN GRCNVQHGNL 
        70         80         90        100        110        120 
GSETSRYLSD LFTTLVDLKW RWNLFIFILT YTVAWLFMAS MWWVIAYTRG DLNKAHVGNY 
       130        140        150        160        170        180 
TPCVANVYNF PSAFLFFIET EATIGYGYRY ITDKCPEGII LFLFQSILGS IVDAFLIGCM 
       190        200        210        220        230        240 
FIKMSQPKKR AETLMFSEHA VISMRDGKLT LMFRVGNLRN SHMVSAQIRC KLLKSRQTPE 
       250        260        270        280        290        300 
GEFLPLDQLE LDVGFSTGAD QLFLVSPLTI CHVIDAKSPF YDLSQRSMQT EQFEIVVILE 
       310        320        330        340        350        360 
GIVETTGMTC QARTSYTEDE VLWGHRFFPV ISLEEGFFKV DYSQFHATFE VPTPPYSVKE 
       370        380        390        400        410        420 
QEEMLLMSSP LIAPAITNSK ERHNSVECLD GLDDITTKLP SKLQKITGRE DFPKKLLRMS 
       430        440        450        460        470        480 
STTSEKAYSL GDLPMKLQRI SSVPGNSEEK LVSKTTKMLS DPMSQSVADL PPKLQKMAGG 
       490        500    
AARMEGNLPA KLRKMNSDRF T



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P48549-1-unknown MSALRR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P48549-1-unknown MSALRR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt78767

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SDRFT 501 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)