P48722: Heat shock 70 kDa protein 4L

General Information

Protein names	- Heat shock 70 kDa protein 4L - Heat shock 70-related protein APG-1 - Osmotic stress protein 94
Gene names	Hspa4l
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P48722

4 N-termini

4 C-termini

3 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSVVGIDLGF LNCYIAVARS GGIETIANEY SDRCTPACIS LGSRTRAIGN AAKSQIVTNV
        70         80         90        100        110        120
RNTIHGFKKL HGRSFDDPIV QTERIRLPYE LQKMPNGSTG VKVRYLEEER PFAIEQVTGM
       130        140        150        160        170        180
LLAKLKETSE NALKKPVADC VISIPSFFTD AERRSVMAAA QVAGLNCLRL MNETTAVALA
       190        200        210        220        230        240
YGIYKQDLPS LDEKPRNVVF IDMGHSAYQV SVCAFNKGKL KVLATTFDPY LGGRNFDEAL
       250        260        270        280        290        300
VDYFCDEFKT KYKINVKENS RALLRLYQEC EKLKKLMSAN ASDLPLNIEC FMNDLDVSSK
       310        320        330        340        350        360
MNRAQFEQLC ASLLARVEPP LKSVMDQANL QREDINSIEI VGGATRIPAV KEQVTRFFLK
       370        380        390        400        410        420
DISTTLNADE AVARGCALQC AILSPAFKVR EFSITDLVPY SVTLRWKTSF EEGTGECEVF
       430        440        450        460        470        480
SKNHPAPFSK VITFHKKEPF ELEAFYTNLH EVPYPDPRIG NFTIQNVFPQ SDGDSSKVKV
       490        500        510        520        530        540
KVRINIHGIF SVASASVIEK QNLEGDHNDA AMETEAPKSE GKEDVDKMQV DQEEGGHQKC
       550        560        570        580        590        600
HAEHTPEEEI DHTGAKAKAP PSDKQDRINQ TIKKGKIKSI DLPIQSSLYR QLTQDLLNSY
       610        620        630        640        650        660
IENEGKMIMQ DKLEKERNDA KNAVEEYVYD FRDKLGTVYE KFITPEDMNK LSAMLEDTEN
       670        680        690        700        710        720
WLYEEGEDQP KQVYVDRLQE LKKYGQPIQM KYVEHEERPK ALNDLGKKIQ LVLKVIEAHR
       730        740        750        760        770        780
NKDERYDHLD PAEMERVEKY ISDSMNWLNS KMNAQNKLSL TQDPVVKVSE IVTKSKELDN
       790        800        810        820        830
FCNPIVYKPK PKVEAPEDKA KTGSEHNGPM DGQSGSETSP DPPKGSSQHT DSGEMEVD

Isoforms

- Isoform 2 of Heat shock 70 kDa protein 4L

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 4 C-termini - 3 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P48722-1-unknown	MSVVGI...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P48722-26-unknown	IANEYS...	26	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30004
P48722-338-unknown	IEIVGG...	338	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30005
P48722-338-unknown	IEIVGG...	338	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt150263
P48722-381-unknown	AILSPA...	381	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30007
P48722-381-unknown	AILSPA...	381	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt151159

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GGIETI	25	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30004
...EDINSI	337	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30005
...EDINSI	337	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt133656
...CALQCA	380	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC30007
...CALQCA	380	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt134561
...EMEVD	838	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EMEVD	838	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt72901

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Evidence name
CATE_MOUSE	25	IETI.\|.IANE	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> HS74L_MOUSE @25
CATE_MOUSE	337	INSI.\|.IEIV	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> HS74L_MOUSE @337
CATE_MOUSE	380	LQCA.\|.AILS	inferred from experiment	unknown	MEROPS	Merops CATE_MOUSE -> HS74L_MOUSE @380

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)