TopFIND 4.0

P49282: Natural resistance-associated macrophage protein 2

General Information

Protein names
- Natural resistance-associated macrophage protein 2
- NRAMP 2
- Divalent cation transporter 1
- Divalent metal transporter 1
- DMT-1
- Solute carrier family 11 member 2
Gene names Slc11a2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P49282

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVLDPKEKMP DDGASGDHGD SASLGAINPA YSNSSLPHST GDSEEPFTTY FDEKIPIPEE 
        70         80         90        100        110        120 
EYSCFSFRKL WAFTGPGFLM SIAYLDPGNI ESDLQSGAVA GFKLLWVLLL ATIVGLLLQR 
       130        140        150        160        170        180 
LAARLGVVTG LHLAEVCHRQ YPKVPRIILW LMVELAIIGS DMQEVIGSAI AINLLSAGRV 
       190        200        210        220        230        240 
PLWGGVLITI ADTFVFLFLD KYGLRKLEAF FGFLITIMAL TFGYEYITVK PSQSQVLRGM 
       250        260        270        280        290        300 
FVPSCPGCRT PQVEQAVGIV GAVIMPHNMY LHSALVKSRQ VNRANKQEVR EANKYFFIES 
       310        320        330        340        350        360 
CIALFVSFII NVFVVSVFAE AFFEKTNKQV VEVCKNNSSP HADLFPSDNS TLAVDIYKGG 
       370        380        390        400        410        420 
VVLGCYFGPA ALYIWAVGIL AAGQSSTMTG TYSGQFVMEG FLNLKWSRFA RVILTRSIAI 
       430        440        450        460        470        480 
IPTLLVAVFQ DVEHLTGMND FLNVLQSLQL PFALIPILTF TSLRPVMSEF SNGIGWRIAG 
       490        500        510        520        530        540 
GILVLIVCSI NMYFVVVYVQ ELGHVALYVV AAVVSVAYLT FVFYLGWQCL IALGLSFLDC 
       550        560    
GRSYRLGLTA QPELYLLNTV DADSVVSR

Isoforms

- Isoform 1 of Natural resistance-associated macrophage protein 2 - Isoform 3 of Natural resistance-associated macrophage protein 2 - Isoform 4 of Natural resistance-associated macrophage protein 2

Sequence View

        10         20         30         40         50         60 
MVLDPKEKMP DDGASGDHGD SASLGAINPA YSNSSLPHST GDSEEPFTTY FDEKIPIPEE 
        70         80         90        100        110        120 
EYSCFSFRKL WAFTGPGFLM SIAYLDPGNI ESDLQSGAVA GFKLLWVLLL ATIVGLLLQR 
       130        140        150        160        170        180 
LAARLGVVTG LHLAEVCHRQ YPKVPRIILW LMVELAIIGS DMQEVIGSAI AINLLSAGRV 
       190        200        210        220        230        240 
PLWGGVLITI ADTFVFLFLD KYGLRKLEAF FGFLITIMAL TFGYEYITVK PSQSQVLRGM 
       250        260        270        280        290        300 
FVPSCPGCRT PQVEQAVGIV GAVIMPHNMY LHSALVKSRQ VNRANKQEVR EANKYFFIES 
       310        320        330        340        350        360 
CIALFVSFII NVFVVSVFAE AFFEKTNKQV VEVCKNNSSP HADLFPSDNS TLAVDIYKGG 
       370        380        390        400        410        420 
VVLGCYFGPA ALYIWAVGIL AAGQSSTMTG TYSGQFVMEG FLNLKWSRFA RVILTRSIAI 
       430        440        450        460        470        480 
IPTLLVAVFQ DVEHLTGMND FLNVLQSLQL PFALIPILTF TSLRPVMSEF SNGIGWRIAG 
       490        500        510        520        530        540 
GILVLIVCSI NMYFVVVYVQ ELGHVALYVV AAVVSVAYLT FVFYLGWQCL IALGLSFLDC 
       550        560    
GRSYRLGLTA QPELYLLNTV DADSVVSR         10         20         30         40         50         60 
MVLDPKEKMP DDGASGDHGD SASLGAINPA YSNSSLPHST GDSEEPFTTY FDEKIPIPEE 
        70         80         90        100        110        120 
EYSCFSFRKL WAFTGPGFLM SIAYLDPGNI ESDLQSGAVA GFKLLWVLLL ATIVGLLLQR 
       130        140        150        160        170        180 
LAARLGVVTG LHLAEVCHRQ YPKVPRIILW LMVELAIIGS DMQEVIGSAI AINLLSAGRV 
       190        200        210        220        230        240 
PLWGGVLITI ADTFVFLFLD KYGLRKLEAF FGFLITIMAL TFGYEYITVK PSQSQVLRGM 
       250        260        270        280        290        300 
FVPSCPGCRT PQVEQAVGIV GAVIMPHNMY LHSALVKSRQ VNRANKQEVR EANKYFFIES 
       310        320        330        340        350        360 
CIALFVSFII NVFVVSVFAE AFFEKTNKQV VEVCKNNSSP HADLFPSDNS TLAVDIYKGG 
       370        380        390        400        410        420 
VVLGCYFGPA ALYIWAVGIL AAGQSSTMTG TYSGQFVMEG FLNLKWSRFA RVILTRSIAI 
       430        440        450        460        470        480 
IPTLLVAVFQ DVEHLTGMND FLNVLQSLQL PFALIPILTF TSLRPVMSEF SNGIGWRIAG 
       490        500        510        520        530        540 
GILVLIVCSI NMYFVVVYVQ ELGHVALYVV AAVVSVAYLT FVFYLGWQCL IALGLSFLDC 
       550        560    
GRSYRLGLTA QPELYLLNTV DADSVVSR         10         20         30         40         50         60 
MVLDPKEKMP DDGASGDHGD SASLGAINPA YSNSSLPHST GDSEEPFTTY FDEKIPIPEE 
        70         80         90        100        110        120 
EYSCFSFRKL WAFTGPGFLM SIAYLDPGNI ESDLQSGAVA GFKLLWVLLL ATIVGLLLQR 
       130        140        150        160        170        180 
LAARLGVVTG LHLAEVCHRQ YPKVPRIILW LMVELAIIGS DMQEVIGSAI AINLLSAGRV 
       190        200        210        220        230        240 
PLWGGVLITI ADTFVFLFLD KYGLRKLEAF FGFLITIMAL TFGYEYITVK PSQSQVLRGM 
       250        260        270        280        290        300 
FVPSCPGCRT PQVEQAVGIV GAVIMPHNMY LHSALVKSRQ VNRANKQEVR EANKYFFIES 
       310        320        330        340        350        360 
CIALFVSFII NVFVVSVFAE AFFEKTNKQV VEVCKNNSSP HADLFPSDNS TLAVDIYKGG 
       370        380        390        400        410        420 
VVLGCYFGPA ALYIWAVGIL AAGQSSTMTG TYSGQFVMEG FLNLKWSRFA RVILTRSIAI 
       430        440        450        460        470        480 
IPTLLVAVFQ DVEHLTGMND FLNVLQSLQL PFALIPILTF TSLRPVMSEF SNGIGWRIAG 
       490        500        510        520        530        540 
GILVLIVCSI NMYFVVVYVQ ELGHVALYVV AAVVSVAYLT FVFYLGWQCL IALGLSFLDC 
       550        560    
GRSYRLGLTA QPELYLLNTV DADSVVSR



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SVVSR 568 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SVVSR 568 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78851

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)