TopFIND 4.0

P49450: Histone H3-like centromeric protein A

General Information

Protein names
- Histone H3-like centromeric protein A
- Centromere autoantigen A
- Centromere protein A
- CENP-A
Gene names CENPA
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P49450

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGPRRRSRKP EAPRRRSPSP TPTPGPSRRG PSLGASSHQH SRRRQGWLKE IRKLQKSTHL 
        70         80         90        100        110        120 
LIRKLPFSRL AREICVKFTR GVDFNWQAQA LLALQEAAEA FLVHLFEDAY LLTLHAGRVT 
       130        140    
LFPKDVQLAR RIRGLEEGLG 

Isoforms

- Isoform 2 of Histone H3-like centromeric protein A

Sequence View

        10         20         30         40         50         60 
MGPRRRSRKP EAPRRRSPSP TPTPGPSRRG PSLGASSHQH SRRRQGWLKE IRKLQKSTHL 
        70         80         90        100        110        120 
LIRKLPFSRL AREICVKFTR GVDFNWQAQA LLALQEAAEA FLVHLFEDAY LLTLHAGRVT 
       130        140    
LFPKDVQLAR RIRGLEEGLG 



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Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P49450-1-unknown MGPRRR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P49450-1-unknown MGPRRR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt70291

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EEGLG 140 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EEGLG 140 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt65909

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)