TopFIND 4.0

P49753: Acyl-coenzyme A thioesterase 2, mitochondrial

General Information

Protein names
- Acyl-coenzyme A thioesterase 2, mitochondrial
- Acyl-CoA thioesterase 2
- 3.1.2.2 {ECO:0000269|PubMed:10944470, ECO:0000269|PubMed:16940157}
- Acyl-coenzyme A thioester hydrolase 2a
- CTE-Ia
- Long-chain acyl-CoA thioesterase 2
- ZAP128
Gene names ACOT2
Organism Homo sapiens
Protease Family
Protease ID S09.028
Chromosome location
UniProt ID P49753

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSNKLLSPHP HSVVLRSEFK MASSPAVLRA SRLYQWSLKS SAQFLGSPQL RQVGQIIRVP 
        70         80         90        100        110        120 
ARMAATLILE PAGRCCWDEP VRIAVRGLAP EQPVTLRASL RDEKGALFQA HARYRADTLG 
       130        140        150        160        170        180 
ELDLERAPAL GGSFAGLEPM GLLWALEPEK PLVRLVKRDV RTPLAVELEV LDGHDPDPGR 
       190        200        210        220        230        240 
LLCQTRHERY FLPPGVRREP VRVGRVRGTL FLPPEPGPFP GIVDMFGTGG GLLEYRASLL 
       250        260        270        280        290        300 
AGKGFAVMAL AYYNYEDLPK TMETLHLEYF EEAMNYLLSH PEVKGPGVGL LGISKGGELC 
       310        320        330        340        350        360 
LSMASFLKGI TAAVVINGSV ANVGGTLHYK GETLPPVGVN RNRIKVTKDG YADIVDVLNS 
       370        380        390        400        410        420 
PLEGPDQKSF IPVERAESTF LFLVGQDDHN WKSEFYANEA CKRLQAHGRR KPQIICYPET 
       430        440        450        460        470        480 
GHYIEPPYFP LCRASLHALV GSPIIWGGEP RAHAMAQVDA WKQLQTFFHK HLGGHEGTIP 
   
SKV

Isoforms

- Isoform 2 of Acyl-coenzyme A thioesterase 2, mitochondrial

Sequence View

        10         20         30         40         50         60 
MSNKLLSPHP HSVVLRSEFK MASSPAVLRA SRLYQWSLKS SAQFLGSPQL RQVGQIIRVP 
        70         80         90        100        110        120 
ARMAATLILE PAGRCCWDEP VRIAVRGLAP EQPVTLRASL RDEKGALFQA HARYRADTLG 
       130        140        150        160        170        180 
ELDLERAPAL GGSFAGLEPM GLLWALEPEK PLVRLVKRDV RTPLAVELEV LDGHDPDPGR 
       190        200        210        220        230        240 
LLCQTRHERY FLPPGVRREP VRVGRVRGTL FLPPEPGPFP GIVDMFGTGG GLLEYRASLL 
       250        260        270        280        290        300 
AGKGFAVMAL AYYNYEDLPK TMETLHLEYF EEAMNYLLSH PEVKGPGVGL LGISKGGELC 
       310        320        330        340        350        360 
LSMASFLKGI TAAVVINGSV ANVGGTLHYK GETLPPVGVN RNRIKVTKDG YADIVDVLNS 
       370        380        390        400        410        420 
PLEGPDQKSF IPVERAESTF LFLVGQDDHN WKSEFYANEA CKRLQAHGRR KPQIICYPET 
       430        440        450        460        470        480 
GHYIEPPYFP LCRASLHALV GSPIIWGGEP RAHAMAQVDA WKQLQTFFHK HLGGHEGTIP 
   
SKV



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...IPSKV 483 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...IPSKV 483 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt61796

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)