TopFIND 4.0

P49760: Dual specificity protein kinase CLK2

General Information

Protein names
- Dual specificity protein kinase CLK2
- 2.7.12.1
- CDC-like kinase 2
Gene names CLK2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P49760

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPHPRRYHSS ERGSRGSYRE HYRSRKHKRR RSRSWSSSSD RTRRRRREDS YHVRSRSSYD 
        70         80         90        100        110        120 
DRSSDRRVYD RRYCGSYRRN DYSRDRGDAY YDTDYRHSYE YQRENSSYRS QRSSRRKHRR 
       130        140        150        160        170        180 
RRRRSRTFSR SSSQHSSRRA KSVEDDAEGH LIYHVGDWLQ ERYEIVSTLG EGTFGRVVQC 
       190        200        210        220        230        240 
VDHRRGGARV ALKIIKNVEK YKEAARLEIN VLEKINEKDP DNKNLCVQMF DWFDYHGHMC 
       250        260        270        280        290        300 
ISFELLGLST FDFLKDNNYL PYPIHQVRHM AFQLCQAVKF LHDNKLTHTD LKPENILFVN 
       310        320        330        340        350        360 
SDYELTYNLE KKRDERSVKS TAVRVVDFGS ATFDHEHHST IVSTRHYRAP EVILELGWSQ 
       370        380        390        400        410        420 
PCDVWSIGCI IFEYYVGFTL FQTHDNREHL AMMERILGPI PSRMIRKTRK QKYFYRGRLD 
       430        440        450        460        470        480 
WDENTSAGRY VRENCKPLRR YLTSEAEEHH QLFDLIESML EYEPAKRLTL GEALQHPFFA 
       490    
RLRAEPPNKL WDSSRDISR

Isoforms

- Isoform 2 of Dual specificity protein kinase CLK2 - Isoform 3 of Dual specificity protein kinase CLK2

Sequence View

        10         20         30         40         50         60 
MPHPRRYHSS ERGSRGSYRE HYRSRKHKRR RSRSWSSSSD RTRRRRREDS YHVRSRSSYD 
        70         80         90        100        110        120 
DRSSDRRVYD RRYCGSYRRN DYSRDRGDAY YDTDYRHSYE YQRENSSYRS QRSSRRKHRR 
       130        140        150        160        170        180 
RRRRSRTFSR SSSQHSSRRA KSVEDDAEGH LIYHVGDWLQ ERYEIVSTLG EGTFGRVVQC 
       190        200        210        220        230        240 
VDHRRGGARV ALKIIKNVEK YKEAARLEIN VLEKINEKDP DNKNLCVQMF DWFDYHGHMC 
       250        260        270        280        290        300 
ISFELLGLST FDFLKDNNYL PYPIHQVRHM AFQLCQAVKF LHDNKLTHTD LKPENILFVN 
       310        320        330        340        350        360 
SDYELTYNLE KKRDERSVKS TAVRVVDFGS ATFDHEHHST IVSTRHYRAP EVILELGWSQ 
       370        380        390        400        410        420 
PCDVWSIGCI IFEYYVGFTL FQTHDNREHL AMMERILGPI PSRMIRKTRK QKYFYRGRLD 
       430        440        450        460        470        480 
WDENTSAGRY VRENCKPLRR YLTSEAEEHH QLFDLIESML EYEPAKRLTL GEALQHPFFA 
       490    
RLRAEPPNKL WDSSRDISR         10         20         30         40         50         60 
MPHPRRYHSS ERGSRGSYRE HYRSRKHKRR RSRSWSSSSD RTRRRRREDS YHVRSRSSYD 
        70         80         90        100        110        120 
DRSSDRRVYD RRYCGSYRRN DYSRDRGDAY YDTDYRHSYE YQRENSSYRS QRSSRRKHRR 
       130        140        150        160        170        180 
RRRRSRTFSR SSSQHSSRRA KSVEDDAEGH LIYHVGDWLQ ERYEIVSTLG EGTFGRVVQC 
       190        200        210        220        230        240 
VDHRRGGARV ALKIIKNVEK YKEAARLEIN VLEKINEKDP DNKNLCVQMF DWFDYHGHMC 
       250        260        270        280        290        300 
ISFELLGLST FDFLKDNNYL PYPIHQVRHM AFQLCQAVKF LHDNKLTHTD LKPENILFVN 
       310        320        330        340        350        360 
SDYELTYNLE KKRDERSVKS TAVRVVDFGS ATFDHEHHST IVSTRHYRAP EVILELGWSQ 
       370        380        390        400        410        420 
PCDVWSIGCI IFEYYVGFTL FQTHDNREHL AMMERILGPI PSRMIRKTRK QKYFYRGRLD 
       430        440        450        460        470        480 
WDENTSAGRY VRENCKPLRR YLTSEAEEHH QLFDLIESML EYEPAKRLTL GEALQHPFFA 
       490    
RLRAEPPNKL WDSSRDISR



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P49760-1-unknown MPHPRR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P49760-1-unknown MPHPRR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt70976
    P49760-1-unknown MPHPRR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt70977

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RDISR 499 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RDISR 499 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt66595

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)