TopFIND 4.0

P49771: Fms-related tyrosine kinase 3 ligand

General Information

Protein names
- Fms-related tyrosine kinase 3 ligand
- Flt3 ligand
- Flt3L
- SL cytokine
Gene names FLT3LG
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P49771

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MTVLAPAWSP TTYLLLLLLL SSGLSGTQDC SFQHSPISSD FAVKIRELSD YLLQDYPVTV 
        70         80         90        100        110        120 
ASNLQDEELC GGLWRLVLAQ RWMERLKTVA GSKMQGLLER VNTEIHFVTK CAFQPPPSCL 
       130        140        150        160        170        180 
RFVQTNISRL LQETSEQLVA LKPWITRQNF SRCLELQCQP DSSTLPPPWS PRPLEATAPT 
       190        200        210        220        230    
APQPPLLLLL LLPVGLLLLA AAWCLHWQRT RRRTPRPGEQ VPPVPSPQDL LLVEH

Isoforms

- Isoform 2 of Fms-related tyrosine kinase 3 ligand - Isoform 3 of Fms-related tyrosine kinase 3 ligand

Sequence View

        10         20         30         40         50         60 
MTVLAPAWSP TTYLLLLLLL SSGLSGTQDC SFQHSPISSD FAVKIRELSD YLLQDYPVTV 
        70         80         90        100        110        120 
ASNLQDEELC GGLWRLVLAQ RWMERLKTVA GSKMQGLLER VNTEIHFVTK CAFQPPPSCL 
       130        140        150        160        170        180 
RFVQTNISRL LQETSEQLVA LKPWITRQNF SRCLELQCQP DSSTLPPPWS PRPLEATAPT 
       190        200        210        220        230    
APQPPLLLLL LLPVGLLLLA AAWCLHWQRT RRRTPRPGEQ VPPVPSPQDL LLVEH         10         20         30         40         50         60 
MTVLAPAWSP TTYLLLLLLL SSGLSGTQDC SFQHSPISSD FAVKIRELSD YLLQDYPVTV 
        70         80         90        100        110        120 
ASNLQDEELC GGLWRLVLAQ RWMERLKTVA GSKMQGLLER VNTEIHFVTK CAFQPPPSCL 
       130        140        150        160        170        180 
RFVQTNISRL LQETSEQLVA LKPWITRQNF SRCLELQCQP DSSTLPPPWS PRPLEATAPT 
       190        200        210        220        230    
APQPPLLLLL LLPVGLLLLA AAWCLHWQRT RRRTPRPGEQ VPPVPSPQDL LLVEH



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Evidence Codes:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LLVEH 235 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LLVEH 235 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt70893

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)