P49902: Cytosolic purine 5'-nucleotidase

General Information

Protein names	- Cytosolic purine 5'-nucleotidase - 3.1.3.5 - Cytosolic 5'-nucleotidase II
Gene names	NT5C2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P49902

4 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSTSWSDRLQ NAADMPANMD KHALKKYRRE AYHRVFVNRS LAMEKIKCFG FDMDYTLAVY
        70         80         90        100        110        120
KSPEYESLGF ELTVERLVSI GYPQELLSFA YDSTFPTRGL VFDTLYGNLL KVDAYGNLLV
       130        140        150        160        170        180
CAHGFNFIRG PETREQYPNK FIQRDDTERF YILNTLFNLP ETYLLACLVD FFTNCPRYTS
       190        200        210        220        230        240
CETGFKDGDL FMSYRSMFQD VRDAVDWVHY KGSLKEKTVE NLEKYVVKDG KLPLLLSRMK
       250        260        270        280        290        300
EVGKVFLATN SDYKYTDKIM TYLFDFPHGP KPGSSHRPWQ SYFDLILVDA RKPLFFGEGT
       310        320        330        340        350        360
VLRQVDTKTG KLKIGTYTGP LQHGIVYSGG SSDTICDLLG AKGKDILYIG DHIFGDILKS
       370        380        390        400        410        420
KKRQGWRTFL VIPELAQELH VWTDKSSLFE ELQSLDIFLA ELYKHLDSSS NERPDISSIQ
       430        440        450        460        470        480
RRIKKVTHDM DMCYGMMGSL FRSGSRQTLF ASQVMRYADL YAASFINLLY YPFSYLFRAA
       490        500        510        520        530        540
HVLMPHESTV EHTHVDINEM ESPLATRNRT SVDFKDTDYK RHQLTRSISE IKPPNLFPLA
       550        560
PQEITHCHDE DDDEEEEEEE E

Isoforms

- Isoform 2 of Cytosolic purine 5'-nucleotidase

Sequence View

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Protein Neighborhood

Domains & Features

4 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P49902-1-unknown	MSTSWS...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P49902-2-acetylation	STSWSD...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P49902-78-unknown	VSIGYP...	78		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000411330
P49902-78-unknown	VSIGYP...	78		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt131324
P49902-301-unknown	VLRQVD...	301		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000408112
P49902-301-unknown	VLRQVD...	301		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt131322

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ESPLAT	505	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000408112
...ESPLAT	505	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt111579
...EEEEE	561	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...EEEEE	561	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt61447

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)