TopFIND 4.0

P50171: Estradiol 17-beta-dehydrogenase 8

General Information

Protein names
- Estradiol 17-beta-dehydrogenase 8
- 1.1.1.62 {ECO:0000269|PubMed:9712896}
- 17-beta-hydroxysteroid dehydrogenase 8
- 17-beta-HSD 8
- 3-ketoacyl-acyl-carrier-protein] reductase alpha subunit {ECO:0000250|UniProtKB:Q92506}
- KAR alpha subunit {ECO:0000250|UniProtKB:Q92506}
- 3-oxoacyl-acyl-carrier-protein] reductase
- 1.1.1.- {ECO:0000250|UniProtKB:Q92506}
- Protein Ke6
- Ke-6
- Testosterone 17-beta-dehydrogenase 8
- 1.1.1.239 {ECO:0000269|PubMed:9712896}
Gene names Hsd17b8
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P50171

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASQLRLRSA LALVTGAGSG IGRAISVRLA AEGAAVAACD LDGAAAQDTV RLLGSPGSED 
        70         80         90        100        110        120 
GAPRGKHAAF QADVSQGPAA RRLLEEVQAC FSRPPSVVVS CAGITRDEFL LHMSEEDWDR 
       130        140        150        160        170        180 
VIAVNLKGTF LVTQAAAQAL VSSGGRGSII NISSIIGKVG NIGQTNYASS KAGVIGLTQT 
       190        200        210        220        230        240 
AARELGRHGI RCNSVLPGFI ATPMTQKMPE KVKDKVTAMI PLGHMGDPED VADVVAFLAS 
       250    
EDSGYITGAS VEVSGGLFM

Isoforms

- Isoform Long of Estradiol 17-beta-dehydrogenase 8

Sequence View

        10         20         30         40         50         60 
MASQLRLRSA LALVTGAGSG IGRAISVRLA AEGAAVAACD LDGAAAQDTV RLLGSPGSED 
        70         80         90        100        110        120 
GAPRGKHAAF QADVSQGPAA RRLLEEVQAC FSRPPSVVVS CAGITRDEFL LHMSEEDWDR 
       130        140        150        160        170        180 
VIAVNLKGTF LVTQAAAQAL VSSGGRGSII NISSIIGKVG NIGQTNYASS KAGVIGLTQT 
       190        200        210        220        230        240 
AARELGRHGI RCNSVLPGFI ATPMTQKMPE KVKDKVTAMI PLGHMGDPED VADVVAFLAS 
       250    
EDSGYITGAS VEVSGGLFM



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P50171-1-unknown MASQLR... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P50171-1-unknown MASQLR... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt72703

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GGLFM 259 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)