P50172: Corticosteroid 11-beta-dehydrogenase isozyme 1

General Information

Protein names	- Corticosteroid 11-beta-dehydrogenase isozyme 1 - 1.1.1.146 - 11-beta-hydroxysteroid dehydrogenase 1 - 11-DH - 11-beta-HSD1 - 11beta-HSD1A
Gene names	Hsd11b1
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P50172

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAVMKNYLLP ILVLFLAYYY YSTNEEFRPE MLQGKKVIVT GASKGIGREM AYHLSKMGAH
        70         80         90        100        110        120
VVLTARSEEG LQKVVSRCLE LGAASAHYIA GTMEDMTFAE QFIVKAGKLM GGLDMLILNH
       130        140        150        160        170        180
ITQTSLSLFH DDIHSVRRVM EVNFLSYVVM STAALPMLKQ SNGSIAVISS LAGKMTQPMI
       190        200        210        220        230        240
APYSASKFAL DGFFSTIRTE LYITKVNVSI TLCVLGLIDT ETAMKEISGI INAQASPKEE
       250        260        270        280        290
CALEIIKGTA LRKSEVYYDK SPLTPILLGN PGRKIMEFFS LRYYNKDMFV SN

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P50172-2-unknown	AVMKNY...	2	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P50172-2-unknown	AVMKNY...	2	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P50172-31-unknown	MLQGKK...	31	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123849
P50172-50-unknown	MAYHLS...	50	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000124715

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...VSITLC	212	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000124693
	...MFVSN	292	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)