TopFIND 4.0

P50431: Serine hydroxymethyltransferase, cytosolic

General Information

Protein names
- Serine hydroxymethyltransferase, cytosolic
- SHMT
- 2.1.2.1 {ECO:0000250|UniProtKB:P34896}
- Glycine hydroxymethyltransferase
- Serine methylase
Gene names Shmt1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P50431

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MADRDATLWA SHEKMLSQPL KDSDAEVYSI IKKESNRQRV GLELIASENF ASRAVLEALG 
        70         80         90        100        110        120 
SCLNNKYSEG YPGQRYYGGT EFIDELEMLC QKRALQAYHL DPQCWGVNVQ PYSGSPANFA 
       130        140        150        160        170        180 
VYTALVEPHG RIMGLDLPDG GHLTHGFMTD KKKISATSIF FESMPYKVYP ETGYINYDQL 
       190        200        210        220        230        240 
EENASLFHPK LIIAGTSCYS RNLDYARLRK IADDNGAYLM ADMAHISGLV AAGVVPSPFE 
       250        260        270        280        290        300 
HCHVVTTTTH KTLRGCRAGM IFYRKGVRSV DPKTGKETYY ELESLINSAV FPGLQGGPHN 
       310        320        330        340        350        360 
HAIAGVAVAL KQAMTTEFKI YQLQVLANCR ALSDALTELG YKIVTGGSDN HLILMDLRSK 
       370        380        390        400        410        420 
GTDGGRAEKV LEACSIACNK NTCPGDKSAL RPSGLRLGTP ALTSRGLLEE DFQKVAHFIH 
       430        440        450        460        470    
RGIELTLQIQ SHMATKATLK EFKEKLAGDE KIQSAVATLR EEVENFASNF SLPGLPDF

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P50431-1-unknown MADRDA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GLPDF 478 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)