TopFIND 4.0

P51168: Amiloride-sensitive sodium channel subunit beta

General Information

Protein names
- Amiloride-sensitive sodium channel subunit beta
- Beta-NaCH
- Epithelial Na(+) channel subunit beta
- Beta-ENaC
- ENaCB
- Nonvoltage-gated sodium channel 1 subunit beta
- SCNEB
Gene names SCNN1B
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P51168

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MHVKKYLLKG LHRLQKGPGY TYKELLVWYC DNTNTHGPKR IICEGPKKKA MWFLLTLLFA 
        70         80         90        100        110        120 
ALVCWQWGIF IRTYLSWEVS VSLSVGFKTM DFPAVTICNA SPFKYSKIKH LLKDLDELME 
       130        140        150        160        170        180 
AVLERILAPE LSHANATRNL NFSIWNHTPL VLIDERNPHH PMVLDLFGDN HNGLTSSSAS 
       190        200        210        220        230        240 
EKICNAHGCK MAMRLCSLNR TQCTFRNFTS ATQALTEWYI LQATNIFAQV PQQELVEMSY 
       250        260        270        280        290        300 
PGEQMILACL FGAEPCNYRN FTSIFYPHYG NCYIFNWGMT EKALPSANPG TEFGLKLILD 
       310        320        330        340        350        360 
IGQEDYVPFL ASTAGVRLML HEQRSYPFIR DEGIYAMSGT ETSIGVLVDK LQRMGEPYSP 
       370        380        390        400        410        420 
CTVNGSEVPV QNFYSDYNTT YSIQACLRSC FQDHMIRNCN CGHYLYPLPR GEKYCNNRDF 
       430        440        450        460        470        480 
PDWAHCYSDL QMSVAQRETC IGMCKESCND TQYKMTISMA DWPSEASEDW IFHVLSQERD 
       490        500        510        520        530        540 
QSTNITLSRK GIVKLNIYFQ EFNYRTIEES AANNIVWLLS NLGGQFGFWM GGSVLCLIEF 
       550        560        570        580        590        600 
GEIIIDFVWI TIIKLVALAK SLRQRRAQAS YAGPPPTVAE LVEAHTNFGF QPDTAPRSPN 
       610        620        630        640    
TGPYPSEQAL PIPGTPPPNY DSLRLQPLDV IESDSEGDAI 

Isoforms

- Isoform 2 of Amiloride-sensitive sodium channel subunit beta

Sequence View

        10         20         30         40         50         60 
MHVKKYLLKG LHRLQKGPGY TYKELLVWYC DNTNTHGPKR IICEGPKKKA MWFLLTLLFA 
        70         80         90        100        110        120 
ALVCWQWGIF IRTYLSWEVS VSLSVGFKTM DFPAVTICNA SPFKYSKIKH LLKDLDELME 
       130        140        150        160        170        180 
AVLERILAPE LSHANATRNL NFSIWNHTPL VLIDERNPHH PMVLDLFGDN HNGLTSSSAS 
       190        200        210        220        230        240 
EKICNAHGCK MAMRLCSLNR TQCTFRNFTS ATQALTEWYI LQATNIFAQV PQQELVEMSY 
       250        260        270        280        290        300 
PGEQMILACL FGAEPCNYRN FTSIFYPHYG NCYIFNWGMT EKALPSANPG TEFGLKLILD 
       310        320        330        340        350        360 
IGQEDYVPFL ASTAGVRLML HEQRSYPFIR DEGIYAMSGT ETSIGVLVDK LQRMGEPYSP 
       370        380        390        400        410        420 
CTVNGSEVPV QNFYSDYNTT YSIQACLRSC FQDHMIRNCN CGHYLYPLPR GEKYCNNRDF 
       430        440        450        460        470        480 
PDWAHCYSDL QMSVAQRETC IGMCKESCND TQYKMTISMA DWPSEASEDW IFHVLSQERD 
       490        500        510        520        530        540 
QSTNITLSRK GIVKLNIYFQ EFNYRTIEES AANNIVWLLS NLGGQFGFWM GGSVLCLIEF 
       550        560        570        580        590        600 
GEIIIDFVWI TIIKLVALAK SLRQRRAQAS YAGPPPTVAE LVEAHTNFGF QPDTAPRSPN 
       610        620        630        640    
TGPYPSEQAL PIPGTPPPNY DSLRLQPLDV IESDSEGDAI 



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P51168-1-unknown MHVKKY... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P51168-1-unknown MHVKKY... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt96088

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EGDAI 640 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EGDAI 640 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt84711

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)