TopFIND 4.0

P51449: Nuclear receptor ROR-gamma

General Information

Protein names
- Nuclear receptor ROR-gamma
- Nuclear receptor RZR-gamma
- Nuclear receptor subfamily 1 group F member 3
- RAR-related orphan receptor C
- Retinoid-related orphan receptor-gamma
Gene names RORC
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P51449

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDRAPQRQHR ASRELLAAKK THTSQIEVIP CKICGDKSSG IHYGVITCEG CKGFFRRSQR 
        70         80         90        100        110        120 
CNAAYSCTRQ QNCPIDRTSR NRCQHCRLQK CLALGMSRDA VKFGRMSKKQ RDSLHAEVQK 
       130        140        150        160        170        180 
QLQQRQQQQQ EPVVKTPPAG AQGADTLTYT LGLPDGQLPL GSSPDLPEAS ACPPGLLKAS 
       190        200        210        220        230        240 
GSGPSYSNNL AKAGLNGASC HLEYSPERGK AEGRESFYST GSQLTPDRCG LRFEEHRHPG 
       250        260        270        280        290        300 
LGELGQGPDS YGSPSFRSTP EAPYASLTEI EHLVQSVCKS YRETCQLRLE DLLRQRSNIF 
       310        320        330        340        350        360 
SREEVTGYQR KSMWEMWERC AHHLTEAIQY VVEFAKRLSG FMELCQNDQI VLLKAGAMEV 
       370        380        390        400        410        420 
VLVRMCRAYN ADNRTVFFEG KYGGMELFRA LGCSELISSI FDFSHSLSAL HFSEDEIALY 
       430        440        450        460        470        480 
TALVLINAHR PGLQEKRKVE QLQYNLELAF HHHLCKTHRQ SILAKLPPKG KLRSLCSQHV 
       490        500        510    
ERLQIFQHLH PIVVQAAFPP LYKELFSTET ESPVGLSK

Isoforms

- Isoform 2 of Nuclear receptor ROR-gamma

Sequence View

        10         20         30         40         50         60 
MDRAPQRQHR ASRELLAAKK THTSQIEVIP CKICGDKSSG IHYGVITCEG CKGFFRRSQR 
        70         80         90        100        110        120 
CNAAYSCTRQ QNCPIDRTSR NRCQHCRLQK CLALGMSRDA VKFGRMSKKQ RDSLHAEVQK 
       130        140        150        160        170        180 
QLQQRQQQQQ EPVVKTPPAG AQGADTLTYT LGLPDGQLPL GSSPDLPEAS ACPPGLLKAS 
       190        200        210        220        230        240 
GSGPSYSNNL AKAGLNGASC HLEYSPERGK AEGRESFYST GSQLTPDRCG LRFEEHRHPG 
       250        260        270        280        290        300 
LGELGQGPDS YGSPSFRSTP EAPYASLTEI EHLVQSVCKS YRETCQLRLE DLLRQRSNIF 
       310        320        330        340        350        360 
SREEVTGYQR KSMWEMWERC AHHLTEAIQY VVEFAKRLSG FMELCQNDQI VLLKAGAMEV 
       370        380        390        400        410        420 
VLVRMCRAYN ADNRTVFFEG KYGGMELFRA LGCSELISSI FDFSHSLSAL HFSEDEIALY 
       430        440        450        460        470        480 
TALVLINAHR PGLQEKRKVE QLQYNLELAF HHHLCKTHRQ SILAKLPPKG KLRSLCSQHV 
       490        500        510    
ERLQIFQHLH PIVVQAAFPP LYKELFSTET ESPVGLSK



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P51449-1-unknown MDRAPQ... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VGLSK 518 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VGLSK 518 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt83715

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)