TopFIND 4.0

P51480: Cyclin-dependent kinase inhibitor 2A {ECO:0000312|MGI:MGI:104738}

General Information

Protein names
- Cyclin-dependent kinase inhibitor 2A {ECO:0000312|MGI:MGI:104738}
- Cyclin-dependent kinase 4 inhibitor A
- CDK4I
- p16-INK4a
- p16-INK4
Gene names Cdkn2a
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P51480

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MESAADRLAR AAAQGRVHDV RALLEAGVSP NAPNSFGRTP IQVMMMGNVH VAALLLNYGA 
        70         80         90        100        110        120 
DSNCEDPTTF SRPVHDAARE GFLDTLVVLH GSGARLDVRD AWGRLPLDLA QERGHQDIVR 
       130        140        150        160    
YLRSAGCSLC SAGWSLCTAG NVAQTDGHSF SSSTPRALEL RGQSQEQS

Isoforms

- Isoform 2 of Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 - Isoform 2 of Cyclin-dependent kinase inhibitor 2A

Sequence View

        10         20         30         40         50         60 
MESAADRLAR AAAQGRVHDV RALLEAGVSP NAPNSFGRTP IQVMMMGNVH VAALLLNYGA 
        70         80         90        100        110        120 
DSNCEDPTTF SRPVHDAARE GFLDTLVVLH GSGARLDVRD AWGRLPLDLA QERGHQDIVR 
       130        140        150        160    
YLRSAGCSLC SAGWSLCTAG NVAQTDGHSF SSSTPRALEL RGQSQEQS         10         20         30         40         50         60 
MESAADRLAR AAAQGRVHDV RALLEAGVSP NAPNSFGRTP IQVMMMGNVH VAALLLNYGA 
        70         80         90        100        110        120 
DSNCEDPTTF SRPVHDAARE GFLDTLVVLH GSGARLDVRD AWGRLPLDLA QERGHQDIVR 
       130        140        150        160    
YLRSAGCSLC SAGWSLCTAG NVAQTDGHSF SSSTPRALEL RGQSQEQS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P51480-1-unknown MESAAD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P51480-44-unknown MMMGNV... 44 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt69927

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SQEQS 168 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SQEQS 168 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt65545

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)