TopFIND 4.0

P51580: Thiopurine S-methyltransferase {ECO:0000303|PubMed:18484748}

General Information

Protein names
- Thiopurine S-methyltransferase {ECO:0000303|PubMed:18484748}
- 2.1.1.67 {ECO:0000269|PubMed:18484748, ECO:0000269|PubMed:657528}
- Thiopurine methyltransferase {ECO:0000303|PubMed:657528}
Gene names TPMT
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P51580

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDGTRTSLDI EEYSDTEVQK NQVLTLEEWQ DKWVNGKTAF HQEQGHQLLK KHLDTFLKGK 
        70         80         90        100        110        120 
SGLRVFFPLC GKAVEMKWFA DRGHSVVGVE ISELGIQEFF TEQNLSYSEE PITEIPGTKV 
       130        140        150        160        170        180 
FKSSSGNISL YCCSIFDLPR TNIGKFDMIW DRGALVAINP GDRKCYADTM FSLLGKKFQY 
       190        200        210        220        230        240 
LLCVLSYDPT KHPGPPFYVP HAEIERLFGK ICNIRCLEKV DAFEERHKSW GIDCLFEKLY 
   
LLTEK

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P51580-1-unknown MDGTRT... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LLTEK 245 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)