TopFIND 4.0

P51650: Succinate-semialdehyde dehydrogenase, mitochondrial

General Information

Protein names
- Succinate-semialdehyde dehydrogenase, mitochondrial
- 1.2.1.24
- Aldehyde dehydrogenase family 5 member A1
- NAD(+)-dependent succinic semialdehyde dehydrogenase
Gene names Aldh5a1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P51650

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MATCFLLRNF CAARPALRPP GRLLREPAGA QRRSYVGGPA DLHADLLRGD SFVGGRWLPT 
        70         80         90        100        110        120 
PATFPVYDPA SGAKLGTVAD CGVPEARAAV RAAYDAFSSW KEISVKERSS LLRKWYDLMI 
       130        140        150        160        170        180 
QNKDELAKII TAESGKPLKE AQGEILYSAF FLEWFSEEAR RVYGDIIYTS AKDKRGLVLK 
       190        200        210        220        230        240 
QPVGVASIIT PWNFPSAMIT RKVGAALAAG CTVVVKPAED TPYSALALAQ LANQAGIPPG 
       250        260        270        280        290        300 
VYNVIPCSRT KAKEVGEVLC TDPLVSKISF TGSTATGKIL LHHAANSVKR VSMELGGLAP 
       310        320        330        340        350        360 
FIVFDSANVD QAVAGAMASK FRNAGQTCVC SNRFLVQRGI HDSFVTKFAE AMKKSLRVGN 
       370        380        390        400        410        420 
GFEEGTTQGP LINEKAVEKV EKHVNDAVAK GATVVTGGKR HQSGGNFFEP TLLSNVTRDM 
       430        440        450        460        470        480 
LCITEETFGP VAPVIKFDKE EEAVAIANAA DVGLAGYFYS QDPAQIWRVA EQLEVGMVGV 
       490        500        510        520    
NEGLISSVEC PFGGVKQSGL GREGSKYGID EYLEVKYVCY GGL

Isoforms

- Isoform Short of Succinate-semialdehyde dehydrogenase, mitochondrial

Sequence View

        10         20         30         40         50         60 
MATCFLLRNF CAARPALRPP GRLLREPAGA QRRSYVGGPA DLHADLLRGD SFVGGRWLPT 
        70         80         90        100        110        120 
PATFPVYDPA SGAKLGTVAD CGVPEARAAV RAAYDAFSSW KEISVKERSS LLRKWYDLMI 
       130        140        150        160        170        180 
QNKDELAKII TAESGKPLKE AQGEILYSAF FLEWFSEEAR RVYGDIIYTS AKDKRGLVLK 
       190        200        210        220        230        240 
QPVGVASIIT PWNFPSAMIT RKVGAALAAG CTVVVKPAED TPYSALALAQ LANQAGIPPG 
       250        260        270        280        290        300 
VYNVIPCSRT KAKEVGEVLC TDPLVSKISF TGSTATGKIL LHHAANSVKR VSMELGGLAP 
       310        320        330        340        350        360 
FIVFDSANVD QAVAGAMASK FRNAGQTCVC SNRFLVQRGI HDSFVTKFAE AMKKSLRVGN 
       370        380        390        400        410        420 
GFEEGTTQGP LINEKAVEKV EKHVNDAVAK GATVVTGGKR HQSGGNFFEP TLLSNVTRDM 
       430        440        450        460        470        480 
LCITEETFGP VAPVIKFDKE EEAVAIANAA DVGLAGYFYS QDPAQIWRVA EQLEVGMVGV 
       490        500        510        520    
NEGLISSVEC PFGGVKQSGL GREGSKYGID EYLEVKYVCY GGL



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P51650-1-unknown MATCFL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt193546
    P51650-36-unknown VGGPAD... 36 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P51650-36-unknown VGGPAD... 36 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt195801

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CYGGL 523 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...CYGGL 523 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt153492

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)