TopFIND 4.0

P51827: AF4/FMR2 family member 3

General Information

Protein names
- AF4/FMR2 family member 3
- Lymphoid nuclear protein related to AF4
- Protein LAF-4
Gene names Aff3
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P51827

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDSFDLALLQ EWDLESLWGE DILSQRNDSL VLEVQASASR CRSVYEPDRN ALRRKERERR 
        70         80         90        100        110        120 
SQETQQDSGS FNSGYSLFSE PYKTNKGDEL SNRIQNTLGN YDEMKDFLTD RSNQSHLVGV 
       130        140        150        160        170        180 
PKPGVPQTPV NKIDEHFGAE SRAQPQPSTV CSTASSTPAA VPVQQGKRGA MGWQKAGHPP 
       190        200        210        220        230        240 
SDGQQRAAQQ GSLRTLLGDG VGRQQTRAKQ VCNMETGLQT QERPPAMAAK HGGSGHCVQN 
       250        260        270        280        290        300 
FPPSLASKPS LVQQKPTAYV RPMDGQDQAP DESPKLKSST ETAVHCTAYR GVPANKPESA 
       310        320        330        340        350        360 
RAKAKLAKFS IPKQAEESRS GENNSCVEEI IREMTWLPPL SAIQAPAKVE PSKFPFPNKD 
       370        380        390        400        410        420 
SQLVSSGHSN PKKADAEPGS PDNGASNTST LEDDLKLSSD DEEGEQQAAQ RTALRALADS 
       430        440        450        460        470        480 
SVVQQTNCRG SAPSSKGGGS SSSSGGSSSS SDSESTSGSD SETESSSSSS ESEGSKPPHC 
       490        500        510        520        530        540 
SSPEAEPASS NKWQLDKWLN KVNPHKPPIL IQNESHGPER NQYYTPPVKD EGQDCGKLPE 
       550        560        570        580        590        600 
ICQASLRDKE LKTTCKEEQR PRTANKAPGS KSVKQKSPPA AVAVTAAALP PAVPSAPTES 
       610        620        630        640        650        660 
APAPTRRSAG KKPTRRTERT SAGDGANCHR PEEPVAPDTL GASVVGPLEP PKTRPCGNNR 
       670        680        690        700        710        720 
TGHRKELRSS VTCEKRRTRG LSRIVPKSKE FIETESSSSS SSSDSDLESE QEEYVLSKAP 
       730        740        750        760        770        780 
TTTGSEQRLK EAASSNNNSN SNSSTSRASV GSINARTTSD IAKELEEQFY TLVPFGRNEL 
       790        800        810        820        830        840 
LSPLKDSDEV RSLWVKIDLT LLSRIPEHLS QEPGVLSAPS AKDTDSAPAS HALDAPAEKT 
       850        860        870        880        890        900 
LPKSKRKRKC DNEDDYREIK KVQGRKESAS RLAASTNNTL SGNHCNVNVN SLAIPINKNE 
       910        920        930        940        950        960 
KMLRSPTSPL SDTCKHKYAS EDLTSSSRPH GNGLLTSASS NKEPKAESQL QTIAGDLTKA 
       970        980        990       1000       1010       1020 
SHNSSENGTL HSKSRPQTEP WSPGSNGHRD CKRQKLIFDD MPRSADYFMR EAKRMKHKAD 
      1030       1040       1050       1060       1070       1080 
AMVEKFGKAL NYAEAALSFI ECGNAMEQGP MESKSPYTMY SETVELIRYA MRLKTHSGPN 
      1090       1100       1110       1120       1130       1140 
ATPEDKQLAA LCYRCLALLY WRMFRLKRDH AVKYSKALID YFKNSSKAAQ APSPWGSSGK 
      1150       1160       1170       1180       1190       1200 
STGSPSPMSP NPSPASSVGS QGSLSSSSGL SPSTIVSIPQ RIHQMAANHV SITNSILHSY 
      1210       1220       1230       1240       1250    
DYWEMADNLA KENREFFNDL DLLMGPVTLH SSMEHLVQYS QQGLHWLRSS VHLS

Isoforms

- Isoform 2 of AF4/FMR2 family member 3

Sequence View

        10         20         30         40         50         60 
MDSFDLALLQ EWDLESLWGE DILSQRNDSL VLEVQASASR CRSVYEPDRN ALRRKERERR 
        70         80         90        100        110        120 
SQETQQDSGS FNSGYSLFSE PYKTNKGDEL SNRIQNTLGN YDEMKDFLTD RSNQSHLVGV 
       130        140        150        160        170        180 
PKPGVPQTPV NKIDEHFGAE SRAQPQPSTV CSTASSTPAA VPVQQGKRGA MGWQKAGHPP 
       190        200        210        220        230        240 
SDGQQRAAQQ GSLRTLLGDG VGRQQTRAKQ VCNMETGLQT QERPPAMAAK HGGSGHCVQN 
       250        260        270        280        290        300 
FPPSLASKPS LVQQKPTAYV RPMDGQDQAP DESPKLKSST ETAVHCTAYR GVPANKPESA 
       310        320        330        340        350        360 
RAKAKLAKFS IPKQAEESRS GENNSCVEEI IREMTWLPPL SAIQAPAKVE PSKFPFPNKD 
       370        380        390        400        410        420 
SQLVSSGHSN PKKADAEPGS PDNGASNTST LEDDLKLSSD DEEGEQQAAQ RTALRALADS 
       430        440        450        460        470        480 
SVVQQTNCRG SAPSSKGGGS SSSSGGSSSS SDSESTSGSD SETESSSSSS ESEGSKPPHC 
       490        500        510        520        530        540 
SSPEAEPASS NKWQLDKWLN KVNPHKPPIL IQNESHGPER NQYYTPPVKD EGQDCGKLPE 
       550        560        570        580        590        600 
ICQASLRDKE LKTTCKEEQR PRTANKAPGS KSVKQKSPPA AVAVTAAALP PAVPSAPTES 
       610        620        630        640        650        660 
APAPTRRSAG KKPTRRTERT SAGDGANCHR PEEPVAPDTL GASVVGPLEP PKTRPCGNNR 
       670        680        690        700        710        720 
TGHRKELRSS VTCEKRRTRG LSRIVPKSKE FIETESSSSS SSSDSDLESE QEEYVLSKAP 
       730        740        750        760        770        780 
TTTGSEQRLK EAASSNNNSN SNSSTSRASV GSINARTTSD IAKELEEQFY TLVPFGRNEL 
       790        800        810        820        830        840 
LSPLKDSDEV RSLWVKIDLT LLSRIPEHLS QEPGVLSAPS AKDTDSAPAS HALDAPAEKT 
       850        860        870        880        890        900 
LPKSKRKRKC DNEDDYREIK KVQGRKESAS RLAASTNNTL SGNHCNVNVN SLAIPINKNE 
       910        920        930        940        950        960 
KMLRSPTSPL SDTCKHKYAS EDLTSSSRPH GNGLLTSASS NKEPKAESQL QTIAGDLTKA 
       970        980        990       1000       1010       1020 
SHNSSENGTL HSKSRPQTEP WSPGSNGHRD CKRQKLIFDD MPRSADYFMR EAKRMKHKAD 
      1030       1040       1050       1060       1070       1080 
AMVEKFGKAL NYAEAALSFI ECGNAMEQGP MESKSPYTMY SETVELIRYA MRLKTHSGPN 
      1090       1100       1110       1120       1130       1140 
ATPEDKQLAA LCYRCLALLY WRMFRLKRDH AVKYSKALID YFKNSSKAAQ APSPWGSSGK 
      1150       1160       1170       1180       1190       1200 
STGSPSPMSP NPSPASSVGS QGSLSSSSGL SPSTIVSIPQ RIHQMAANHV SITNSILHSY 
      1210       1220       1230       1240       1250    
DYWEMADNLA KENREFFNDL DLLMGPVTLH SSMEHLVQYS QQGLHWLRSS VHLS



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P51827-1-unknown MDSFDL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P51827-1-unknown MDSFDL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt66475

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QRPRTA 563 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt62093
    ...SVHLS 1254 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)