TopFIND 4.0

P51956: Serine/threonine-protein kinase Nek3

General Information

Protein names
- Serine/threonine-protein kinase Nek3
- 2.7.11.1
- HSPK 36
- Never in mitosis A-related kinase 3
- NimA-related protein kinase 3
Gene names NEK3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P51956

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDDYMVLRMI GEGSFGRALL VQHESSNQMF AMKEIRLPKS FSNTQNSRKE AVLLAKMKHP 
        70         80         90        100        110        120 
NIVAFKESFE AEGHLYIVME YCDGGDLMQK IKQQKGKLFP EDMILNWFTQ MCLGVNHIHK 
       130        140        150        160        170        180 
KRVLHRDIKS KNIFLTQNGK VKLGDFGSAR LLSNPMAFAC TYVGTPYYVP PEIWENLPYN 
       190        200        210        220        230        240 
NKSDIWSLGC ILYELCTLKH PFQANSWKNL ILKVCQGCIS PLPSHYSYEL QFLVKQMFKR 
       250        260        270        280        290        300 
NPSHRPSATT LLSRGIVARL VQKCLPPEII MEYGEEVLEE IKNSKHNTPR KKTNPSRIRI 
       310        320        330        340        350        360 
ALGNEASTVQ EEEQDRKGSH TDLESINENL VESALRRVNR EEKGNKSVHL RKASSPNLHR 
       370        380        390        400        410        420 
RQWEKNVPNT ALTALENASI LTSSLTAEDD RGGSVIKYSK NTTRKQWLKE TPDTLLNILK 
       430        440        450        460        470        480 
NADLSLAFQT YTIYRPGSEG FLKGPLSEET EASDSVDGGH DSVILDPERL EPGLDEEDTD 
       490        500    
FEEEDDNPDW VSELKKRAGW QGLCDR

Isoforms

- Isoform 2 of Serine/threonine-protein kinase Nek3

Sequence View

        10         20         30         40         50         60 
MDDYMVLRMI GEGSFGRALL VQHESSNQMF AMKEIRLPKS FSNTQNSRKE AVLLAKMKHP 
        70         80         90        100        110        120 
NIVAFKESFE AEGHLYIVME YCDGGDLMQK IKQQKGKLFP EDMILNWFTQ MCLGVNHIHK 
       130        140        150        160        170        180 
KRVLHRDIKS KNIFLTQNGK VKLGDFGSAR LLSNPMAFAC TYVGTPYYVP PEIWENLPYN 
       190        200        210        220        230        240 
NKSDIWSLGC ILYELCTLKH PFQANSWKNL ILKVCQGCIS PLPSHYSYEL QFLVKQMFKR 
       250        260        270        280        290        300 
NPSHRPSATT LLSRGIVARL VQKCLPPEII MEYGEEVLEE IKNSKHNTPR KKTNPSRIRI 
       310        320        330        340        350        360 
ALGNEASTVQ EEEQDRKGSH TDLESINENL VESALRRVNR EEKGNKSVHL RKASSPNLHR 
       370        380        390        400        410        420 
RQWEKNVPNT ALTALENASI LTSSLTAEDD RGGSVIKYSK NTTRKQWLKE TPDTLLNILK 
       430        440        450        460        470        480 
NADLSLAFQT YTIYRPGSEG FLKGPLSEET EASDSVDGGH DSVILDPERL EPGLDEEDTD 
       490        500    
FEEEDDNPDW VSELKKRAGW QGLCDR



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GLCDR 506 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...GLCDR 506 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78208

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)