TopFIND 4.0

P51965: Ubiquitin-conjugating enzyme E2 E1

General Information

Protein names
- Ubiquitin-conjugating enzyme E2 E1
- 2.3.2.23 {ECO:0000269|PubMed:20061386}
- (E3-independent) E2 ubiquitin-conjugating enzyme E1
- 2.3.2.24 {ECO:0000269|PubMed:17588522}
- E2 ubiquitin-conjugating enzyme E1
- UbcH6
- Ubiquitin carrier protein E1
- Ubiquitin-protein ligase E1
Gene names UBE2E1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P51965

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSDDDSRAST SSSSSSSSNQ QTEKETNTPK KKESKVSMSK NSKLLSTSAK RIQKELADIT 
        70         80         90        100        110        120 
LDPPPNCSAG PKGDNIYEWR STILGPPGSV YEGGVFFLDI TFTPEYPFKP PKVTFRTRIY 
       130        140        150        160        170        180 
HCNINSQGVI CLDILKDNWS PALTISKVLL SICSLLTDCN PADPLVGSIA TQYMTNRAEH 
       190    
DRMARQWTKR YAT

Isoforms

- Isoform 2 of Ubiquitin-conjugating enzyme E2 E1 - Isoform 3 of Ubiquitin-conjugating enzyme E2 E1

Sequence View

        10         20         30         40         50         60 
MSDDDSRAST SSSSSSSSNQ QTEKETNTPK KKESKVSMSK NSKLLSTSAK RIQKELADIT 
        70         80         90        100        110        120 
LDPPPNCSAG PKGDNIYEWR STILGPPGSV YEGGVFFLDI TFTPEYPFKP PKVTFRTRIY 
       130        140        150        160        170        180 
HCNINSQGVI CLDILKDNWS PALTISKVLL SICSLLTDCN PADPLVGSIA TQYMTNRAEH 
       190    
DRMARQWTKR YAT         10         20         30         40         50         60 
MSDDDSRAST SSSSSSSSNQ QTEKETNTPK KKESKVSMSK NSKLLSTSAK RIQKELADIT 
        70         80         90        100        110        120 
LDPPPNCSAG PKGDNIYEWR STILGPPGSV YEGGVFFLDI TFTPEYPFKP PKVTFRTRIY 
       130        140        150        160        170        180 
HCNINSQGVI CLDILKDNWS PALTISKVLL SICSLLTDCN PADPLVGSIA TQYMTNRAEH 
       190    
DRMARQWTKR YAT



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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P51965-1-unknown MSDDDS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt93548
    P51965-2-unknown MSDDDS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P51965-2-Acetylation SDDDSR... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P51965-2-Acetylation SDDDSR... 2 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt111713

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)