P52293: Importin subunit alpha-1 {ECO:0000305}

General Information

Protein names	- Importin subunit alpha-1 {ECO:0000305} - Importin alpha P1 - Karyopherin subunit alpha-2 - Pendulin - Pore targeting complex 58 kDa subunit - PTAC58 - RAG cohort protein 1 - SRP1-alpha
Gene names	Kpna2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P52293

2 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSTNENANLP AARLNRFKNK GKDSTEMRRR RIEVNVELRK AKKDEQMLKR RNVSSFPDDA
        70         80         90        100        110        120
TSPLQENRNN QGTVNWSVED IVKGINSNNL ESQLQATQAA RKLLSREKQP PIDNIIRAGL
       130        140        150        160        170        180
IPKFVSFLGK TDCSPIQFES AWALTNIASG TSEQTKAVVD GGAIPAFISL LASPHAHISE
       190        200        210        220        230        240
QAVWALGNIA GDGSAFRDLV IKHGAIDPLL ALLAVPDLST LACGYLRNLT WTLSNLCRNK
       250        260        270        280        290        300
NPAPPLDAVE QILPTLVRLL HHNDPEVLAD SCWAISYLTD GPNERIEMVV KKGVVPQLVK
       310        320        330        340        350        360
LLGATELPIV TPALRAIGNI VTGTDEQTQK VIDAGALAVF PSLLTNPKTN IQKEATWTMS
       370        380        390        400        410        420
NITAGRQDQI QQVVNHGLVP FLVGVLSKAD FKTQKEAAWA ITNYTSGGTV EQIVYLVHCG
       430        440        450        460        470        480
IIEPLMNLLS AKDTKIIQVI LDAISNIFQA AEKLGETEKL SIMIEECGGL DKIEALQRHE
       490        500        510        520
NESVYKASLN LIEKYFSVEE EEDQNVVPET TSEGFAFQVQ DGAPGTFNF

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

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Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P52293-2-unknown	MSTNEN...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P52293-2-unknown	MSTNEN...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P52293-2-Acetylation	STNENA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P52293-2-Acetylation	STNENA...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VDGGAI	163	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121655
...AFISLL	170	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118679
...AFISLL	170	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000114636
...GTFNF	529	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)