TopFIND 4.0

P52785: Guanylyl cyclase GC-E

General Information

Protein names
- Guanylyl cyclase GC-E
- 4.6.1.2
- Guanylate cyclase 2E
Gene names Gucy2e
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P52785

2

N-termini

2

C-termini

1

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSAWLLPAGG LPGAGFCVPA RQSPSSFSRV LRWPRPGLPG LLLLLLLPSP SALSAVFKVG 
        70         80         90        100        110        120 
VLGPWACDPI FARARPDLAA RLAANRLNRD FALDGGPRFE VALLPEPCLT PGSLGAVSSA 
       130        140        150        160        170        180 
LSRVSGLVGP VNPAACRPAE LLAQEAGVAL VPWGCPGTRA AGTTAPAVTP AADALYVLLR 
       190        200        210        220        230        240 
AFRWARVALI TAPQDLWVEA GRALSTALRA RGLPVALVTS METSDRSGAR EALGRIRDGP 
       250        260        270        280        290        300 
RVRVVIMVMH SVLLGGEEQR YLLEAAEELA LTDGSLVFLP FDTLHYALSP GPEALAAFVN 
       310        320        330        340        350        360 
SSQLRRAHDA VLTLTRRCPP GGSVQDSLRR AQEHQELPLD LNLKQVSPLF GTIYDAVFLL 
       370        380        390        400        410        420 
AGGVKRARTA VGGGWVSGAS VARQVREAQV SGFCGVLGRT EEPSFVLLDT DASGEQLFAT 
       430        440        450        460        470        480 
HLLDPVLGSL RSAGTPMHFP RGGPAPGPDP SCWFDPDVIC NGGVEPGLVF VGFLLVIGMG 
       490        500        510        520        530        540 
LTGAFLAHYL RHRLLHMQMA SGPNKIILTL EDVTFLHPPG GSSRKVVQGS RSSLATRSAS 
       550        560        570        580        590        600 
DIRSVPSQPQ ESTNVGLYEG DWVWLKKFPG EHHMAIRPAT KTAFSKLREL RHENVALYLG 
       610        620        630        640        650        660 
LFLAGTADSP ATPGEGILAV VSEHCARGSL HDLLAQREIK LDWMFKSSLL LDLIKGMRYL 
       670        680        690        700        710        720 
HHRGVAHGRL KSRNCVVDGR FVLKVTDHGH GRLLEAQRVL PEPPSAEDQL WTAPELLRDP 
       730        740        750        760        770        780 
SLERRGTLAG DVFSLAIIMQ EVVCRSTPYA MLELTPEEVI QRVRSPPPLC RPLVSMDQAP 
       790        800        810        820        830        840 
MECIQLMTQC WAEHPELRPS MDLTFDLFKS INKGRKTNII DSMLRMLEQY SSNLEDLIRE 
       850        860        870        880        890        900 
RTEELEQEKQ KTDRLLTQML PPSVAEALKM GTSVEPEYFE EVTLYFSDIV GFTTISAMSE 
       910        920        930        940        950        960 
PIEVVDLLND LYTLFDAIIG AHDVYKVETI GDAYMVASGL PQRNGQRHAA EIANMSLDIL 
       970        980        990       1000       1010       1020 
SAVGSFRMRH MPEVPVRIRI GLHSGPCVAG VVGLTMPRYC LFGDTVNTAS RMESTGLPYR 
      1030       1040       1050       1060       1070       1080 
IHVNMSTVRI LRALDQGFQM ECRGRTELKG KGIEDTYWLV GRLGFNKPIP KPPDLQPGAS 
      1090       1100    
NHGISLQEIP PERRKKLEKA RPGQFTGK

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P52785-55-unknown AVFKVG... 55 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P52785-203-unknown ALSTAL... 203 inferred from cleavage unknown TopFIND Inferred from cleavage TC30087

C-termini

Cleavages

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)