P53985: Monocarboxylate transporter 1

General Information

Protein names	- Monocarboxylate transporter 1 - MCT 1 - Solute carrier family 16 member 1
Gene names	SLC16A1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P53985

3 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPPAVGGPVG YTPPDGGWGW AVVIGAFISI GFSYAFPKSI TVFFKEIEGI FHATTSEVSW
        70         80         90        100        110        120
ISSIMLAVMY GGGPISSILV NKYGSRIVMI VGGCLSGCGL IAASFCNTVQ QLYVCIGVIG
       130        140        150        160        170        180
GLGLAFNLNP ALTMIGKYFY KRRPLANGLA MAGSPVFLCT LAPLNQVFFG IFGWRGSFLI
       190        200        210        220        230        240
LGGLLLNCCV AGALMRPIGP KPTKAGKDKS KASLEKAGKS GVKKDLHDAN TDLIGRHPKQ
       250        260        270        280        290        300
EKRSVFQTIN QFLDLTLFTH RGFLLYLSGN VIMFFGLFAP LVFLSSYGKS QHYSSEKSAF
       310        320        330        340        350        360
LLSILAFVDM VARPSMGLVA NTKPIRPRIQ YFFAASVVAN GVCHMLAPLS TTYVGFCVYA
       370        380        390        400        410        420
GFFGFAFGWL SSVLFETLMD LVGPQRFSSA VGLVTIVECC PVLLGPPLLG RLNDMYGDYK
       430        440        450        460        470        480
YTYWACGVVL IISGIYLFIG MGINYRLLAK EQKANEQKKE SKEEETSIDV AGKPNEVTKA
       490        500
AESPDQKDTD GGPKEEESPV

Isoforms

- Isoform 2 of Monocarboxylate transporter 1

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P53985-1-unknown	MPPAVG...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P53985-470-unknown	VAGKPN...	470		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P53985-470-	VAGKPN...	470		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P53985-470-	VAGKPN...	470		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KASLEK	215	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000397106
...HYSSEK	296	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000399104
...QKANEQ	456	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000416167
...EESPV	500	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)