TopFIND 4.0

P53995: Anaphase-promoting complex subunit 1

General Information

Protein names
- Anaphase-promoting complex subunit 1
- APC1
- Cyclosome subunit 1
- Mitotic checkpoint regulator
- Testis-specific gene 24 protein
Gene names Anapc1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P53995

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSNFSEERAT MIAAGDLQEF VPFGRDHCKH HPNALNLQLR QLQPASELWS SDGAAGLVGS 
        70         80         90        100        110        120 
LQEVTIHEKQ KESWQLRKGV SEIGDAADYD EELYVAGNMV IWSKGSKSQA LAVYKAFTVD 
       130        140        150        160        170        180 
STVQQALWCD FIISQDKSEK IYKSHELEKC ICILQSSCMN MHSIDGKDYI ASLPFQVANV 
       190        200        210        220        230        240 
WATKYGLLFE RCSSSHEVPP SLPREPLPTM FSMLHPLDEI TPLVCKSGSL FGSSRVQYVV 
       250        260        270        280        290        300 
DPAVKIVFLN IDPSIVMTYD AVQNVHSVWT LRRVKPEEEN AVLKFPEQAG TLQNATTSSS 
       310        320        330        340        350        360 
LTAHLRSLSK GESPVASPFQ NYSSIHSQSR STSSPSLHSR SPSISNMAAL SRAHSPALGV 
       370        380        390        400        410        420 
HSFSGAQRFN LSSHSQSPKR HSISHSPSGS FNDSFLAPET EPIVPELCID HLWTETLPNI 
       430        440        450        460        470        480 
REKNSQASKV FITTDLCGQK FLCFLVEAQL QLRCVKFQES NDKTQLIFGS VTNIHAKDAA 
       490        500        510        520        530        540 
PVEKIHTMLV LEGNGNLVLY TGVVRVGKVF IPGLPAPSLT MSNMMPRPST PLDGVGTPKP 
       550        560        570        580        590        600 
LSKLLGSMDE VVLLSPVPEL RDSSKLNDSL YNEDCTFQQL GTYIHSVRDP VHNRVTLELS 
       610        620        630        640        650        660 
NGSMVRITIP EVATSELVQT CLQAIKFILP KEVAIQVLVK WYNVHSAPGG PSCHSEWSLF 
       670        680        690        700        710        720 
VICLLNMMGY NTDRLAWTRS FDFEGSLSPV IAPKKARPSD TGSDEDWEYL LNSEYHRNVE 
       730        740        750        760        770        780 
SHLLNKSLCL TALEVSNAKD EDFSQNLSLD SSTLLFAHIP AIFFVLHLVY EELKLNTLMG 
       790        800        810        820        830        840 
EGICSLIDLL VQLARDLKLD SYLDHYYRDS PTLVKTTGQV CTIDQGQMGF MHHPPFFTSE 
       850        860        870        880        890        900 
PPSIYQWVSS CLKGEGMPPY PYLPGICERS RLVVLSIALY TLGDESCVSD ETCQYLSKVT 
       910        920        930        940        950        960 
STPQKPQAEQ EENRFTFRHS ASVSVLAERL VVWMASVGFT LRDLETLPFG IALPIRDAIY 
       970        980        990       1000       1010       1020 
HCREQPDSDW SEAVCLLIGR QDLSKQACEG NLPRGKSVLS SEVSSGTEAE EEDDGMNDLN 
      1030       1040       1050       1060       1070       1080 
HEVMSLIWSE DLRVQDVRRL LQSAQPVRVN VVQYPELSDH EFIEEKENRL LQLCQRTMAL 
      1090       1100       1110       1120       1130       1140 
PVGRGMFTLF SYHPVPTEPL PVPKLNLTGR APPRNTTVDL NSGNIDVPPN MASWASFHNG 
      1150       1160       1170       1180       1190       1200 
VAAGLKIAPA SQIDSAWIVY NKPKHAELAN EYAGFLMALG LNGHLTKLAT LNIHDYLTKG 
      1210       1220       1230       1240       1250       1260 
HEMTSIGLLL GVSAAKLGTM DMSITRLLSI HVPALLPPTS TELDVPHNVQ VAAVVGIGLV 
      1270       1280       1290       1300       1310       1320 
YQGTAHRHTA EVLLAEIGRP PGPEMEYCTD RESYSLAAGL ALGMVCLGHG SNLIGMSDLN 
      1330       1340       1350       1360       1370       1380 
VPEQLYQYMV GGHRRFQTGM HREKHKSPSY QIKEGDTINV DVTCPGATLA LAMIYLKTNN 
      1390       1400       1410       1420       1430       1440 
RSIADWLRAP DTMYLLDFVK PEFLLLRTLA RCLILWDDIL PNSKWVDSNV PQIIRENSIS 
      1450       1460       1470       1480       1490       1500 
LSEIELPCSE DLNLETLSQA HVYIIAGACL SLGFRFAGSE NLSAFSCLHK FAKDFMNYLS 
      1510       1520       1530       1540       1550       1560 
APNASVTGPY NLETCLSVVL LSLAMVMAGS GNLKVLQLCR FLHMKTGGEM NYGFHLAHHM 
      1570       1580       1590       1600       1610       1620 
ALGLLFLGGG RYSLSTSNSS IAALLCALYP HFPAHSTDNR YHLQALRHLY VLAAEPRLLV 
      1630       1640       1650       1660       1670       1680 
PVDVDTNTPC YALIEVTYKG TQWYEQTKEE LMAPTLLPEL HLLKQMKVKG PRYWELLIDL 
      1690       1700       1710       1720       1730       1740 
SKGEQHLRSI LSKDGVLYVK LRAGQLSYKE DPMGWQSLLA QTVANRNSEA RAFKPETISS 
      1750       1760       1770       1780       1790       1800 
FTSDPALLSF AEYFCKPTVS MGPKQEILDL FSSILYECVA QETPEMLPAY IAMDQALRSL 
      1810       1820       1830       1840       1850       1860 
KKRDMSDTSD LWQIKLILEF FSSRSHQDRQ HTYPKRGLFI NSEFLPVVKC TVDATLDQWL 
      1870       1880       1890       1900       1910       1920 
QAGGDVCVHA YLSGQPVEKS QLNMLACFLV YHSVPAPRHL PPMGLEGSTS FAELLYRFRH 
      1930       1940    
LKMPVRALLR LAPVLLGNPQ PMVM

Isoforms



Sequence View



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P53995-1-unknown MSNFSE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P53995-11-unknown MIAAGD... 11 inferred from electronic annotation unknown TISdb inferred from TISdb
    P53995-424-unknown NSQASK... 424 inferred from electronic annotation unknown TISdb inferred from TISdb

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QPMVM 1944 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)