TopFIND 4.0

P54219: Chromaffin granule amine transporter

General Information

Protein names
- Chromaffin granule amine transporter
- Solute carrier family 18 member 1
- Vesicular amine transporter 1
- VAT1
Gene names SLC18A1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P54219

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLRTILDAPQ RLLKEGRASR QLVLVVVFVA LLLDNMLFTV VVPIVPTFLY DMEFKEVNSS 
        70         80         90        100        110        120 
LHLGHAGSSP HALASPAFST IFSFFNNNTV AVEESVPSGI AWMNDTASTI PPPATEAISA 
       130        140        150        160        170        180 
HKNNCLQGTG FLEEEITRVG VLFASKAVMQ LLVNPFVGPL TNRIGYHIPM FAGFVIMFLS 
       190        200        210        220        230        240 
TVMFAFSGTY TLLFVARTLQ GIGSSFSSVA GLGMLASVYT DDHERGRAMG TALGGLALGL 
       250        260        270        280        290        300 
LVGAPFGSVM YEFVGKSAPF LILAFLALLD GALQLCILQP SKVSPESAKG TPLFMLLKDP 
       310        320        330        340        350        360 
YILVAAGSIC FANMGVAILE PTLPIWMMQT MCSPKWQLGL AFLPASVSYL IGTNLFGVLA 
       370        380        390        400        410        420 
NKMGRWLCSL IGMLVVGTSL LCVPLAHNIF GLIGPNAGLG LAIGMVDSSM MPIMGHLVDL 
       430        440        450        460        470        480 
RHTSVYGSVY AIADVAFCMG FAIGPSTGGA IVKAIGFPWL MVITGVINIV YAPLCYYLRS 
       490        500        510        520    
PPAKEEKLAI LSQDCPMETR MYATQKPTKE FPLGEDSDEE PDHEE

Isoforms

- Isoform 2 of Chromaffin granule amine transporter - Isoform 3 of Chromaffin granule amine transporter

Sequence View

        10         20         30         40         50         60 
MLRTILDAPQ RLLKEGRASR QLVLVVVFVA LLLDNMLFTV VVPIVPTFLY DMEFKEVNSS 
        70         80         90        100        110        120 
LHLGHAGSSP HALASPAFST IFSFFNNNTV AVEESVPSGI AWMNDTASTI PPPATEAISA 
       130        140        150        160        170        180 
HKNNCLQGTG FLEEEITRVG VLFASKAVMQ LLVNPFVGPL TNRIGYHIPM FAGFVIMFLS 
       190        200        210        220        230        240 
TVMFAFSGTY TLLFVARTLQ GIGSSFSSVA GLGMLASVYT DDHERGRAMG TALGGLALGL 
       250        260        270        280        290        300 
LVGAPFGSVM YEFVGKSAPF LILAFLALLD GALQLCILQP SKVSPESAKG TPLFMLLKDP 
       310        320        330        340        350        360 
YILVAAGSIC FANMGVAILE PTLPIWMMQT MCSPKWQLGL AFLPASVSYL IGTNLFGVLA 
       370        380        390        400        410        420 
NKMGRWLCSL IGMLVVGTSL LCVPLAHNIF GLIGPNAGLG LAIGMVDSSM MPIMGHLVDL 
       430        440        450        460        470        480 
RHTSVYGSVY AIADVAFCMG FAIGPSTGGA IVKAIGFPWL MVITGVINIV YAPLCYYLRS 
       490        500        510        520    
PPAKEEKLAI LSQDCPMETR MYATQKPTKE FPLGEDSDEE PDHEE         10         20         30         40         50         60 
MLRTILDAPQ RLLKEGRASR QLVLVVVFVA LLLDNMLFTV VVPIVPTFLY DMEFKEVNSS 
        70         80         90        100        110        120 
LHLGHAGSSP HALASPAFST IFSFFNNNTV AVEESVPSGI AWMNDTASTI PPPATEAISA 
       130        140        150        160        170        180 
HKNNCLQGTG FLEEEITRVG VLFASKAVMQ LLVNPFVGPL TNRIGYHIPM FAGFVIMFLS 
       190        200        210        220        230        240 
TVMFAFSGTY TLLFVARTLQ GIGSSFSSVA GLGMLASVYT DDHERGRAMG TALGGLALGL 
       250        260        270        280        290        300 
LVGAPFGSVM YEFVGKSAPF LILAFLALLD GALQLCILQP SKVSPESAKG TPLFMLLKDP 
       310        320        330        340        350        360 
YILVAAGSIC FANMGVAILE PTLPIWMMQT MCSPKWQLGL AFLPASVSYL IGTNLFGVLA 
       370        380        390        400        410        420 
NKMGRWLCSL IGMLVVGTSL LCVPLAHNIF GLIGPNAGLG LAIGMVDSSM MPIMGHLVDL 
       430        440        450        460        470        480 
RHTSVYGSVY AIADVAFCMG FAIGPSTGGA IVKAIGFPWL MVITGVINIV YAPLCYYLRS 
       490        500        510        520    
PPAKEEKLAI LSQDCPMETR MYATQKPTKE FPLGEDSDEE PDHEE



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P54219-1-unknown MLRTIL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P54219-1-unknown MLRTIL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94201
    P54219-1-unknown MLRTIL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt94202

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PDHEE 525 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PDHEE 525 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt89820

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)