TopFIND 4.0

P54274: Telomeric repeat-binding factor 1

General Information

Protein names
- Telomeric repeat-binding factor 1
- NIMA-interacting protein 2
- TTAGGG repeat-binding factor 1
- Telomeric protein Pin2/TRF1
Gene names TERF1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P54274

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAEDVSSAAP SPRGCADGRD ADPTEEQMAE TERNDEEQFE CQELLECQVQ VGAPEEEEEE 
        70         80         90        100        110        120 
EEDAGLVAEA EAVAAGWMLD FLCLSLCRAF RDGRSEDFRR TRNSAEAIIH GLSSLTACQL 
       130        140        150        160        170        180 
RTIYICQFLT RIAAGKTLDA QFENDERITP LESALMIWGS IEKEHDKLHE EIQNLIKIQA 
       190        200        210        220        230        240 
IAVCMENGNF KEAEEVFERI FGDPNSHMPF KSKLLMIISQ KDTFHSFFQH FSYNHMMEKI 
       250        260        270        280        290        300 
KSYVNYVLSE KSSTFLMKAA AKVVESKRTR TITSQDKPSG NDVEMETEAN LDTRKSVSDK 
       310        320        330        340        350        360 
QSAVTESSEG TVSLLRSHKN LFLSKLQHGT QQQDLNKKER RVGTPQSTKK KKESRRATES 
       370        380        390        400        410        420 
RIPVSKSQPV TPEKHRARKR QAWLWEEDKN LRSGVRKYGE GNWSKILLHY KFNNRTSVML 
       430    
KDRWRTMKKL KLISSDSED

Isoforms

- Isoform 2 of Telomeric repeat-binding factor 1

Sequence View

        10         20         30         40         50         60 
MAEDVSSAAP SPRGCADGRD ADPTEEQMAE TERNDEEQFE CQELLECQVQ VGAPEEEEEE 
        70         80         90        100        110        120 
EEDAGLVAEA EAVAAGWMLD FLCLSLCRAF RDGRSEDFRR TRNSAEAIIH GLSSLTACQL 
       130        140        150        160        170        180 
RTIYICQFLT RIAAGKTLDA QFENDERITP LESALMIWGS IEKEHDKLHE EIQNLIKIQA 
       190        200        210        220        230        240 
IAVCMENGNF KEAEEVFERI FGDPNSHMPF KSKLLMIISQ KDTFHSFFQH FSYNHMMEKI 
       250        260        270        280        290        300 
KSYVNYVLSE KSSTFLMKAA AKVVESKRTR TITSQDKPSG NDVEMETEAN LDTRKSVSDK 
       310        320        330        340        350        360 
QSAVTESSEG TVSLLRSHKN LFLSKLQHGT QQQDLNKKER RVGTPQSTKK KKESRRATES 
       370        380        390        400        410        420 
RIPVSKSQPV TPEKHRARKR QAWLWEEDKN LRSGVRKYGE GNWSKILLHY KFNNRTSVML 
       430    
KDRWRTMKKL KLISSDSED



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Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P54274-2-unknown MAEDVS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P54274-1-unknown MAEDVS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt91880
    P54274-2-Acetylation AEDVSS... 2 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P54274-2-Acetylation AEDVSS... 2 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt110723

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SDSED 439 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SDSED 439 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt87498

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)