P54829: Tyrosine-protein phosphatase non-receptor type 5

General Information

Protein names	- Tyrosine-protein phosphatase non-receptor type 5 - 3.1.3.48 - Neural-specific protein-tyrosine phosphatase - Striatum-enriched protein-tyrosine phosphatase - STEP
Gene names	PTPN5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P54829

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Tyrosine-protein phosphatase non-receptor type 5 - Isoform 3 of Tyrosine-protein phosphatase non-receptor type 5

Sequence View

        10         20         30         40         50         60
MNYEGARSER ENHAADDSEG GALDMCCSER LPGLPQPIVM EALDEAEGLQ DSQREMPPPP
        70         80         90        100        110        120
PPSPPSDPAQ KPPPRGAGSH SLTVRSSLCL FAASQFLLAC GVLWFSGYGH IWSQNATNLV
       130        140        150        160        170        180
SSLLTLLKQL EPTAWLDSGT WGVPSLLLVF LSVGLVLVTT LVWHLLRTPP EPPTPLPPED
       190        200        210        220        230        240
RRQSVSRQPS FTYSEWMEEK IEDDFLDLDP VPETPVFDCV MDIKPEADPT SLTVKSMGLQ
       250        260        270        280        290        300
ERRGSNVSLT LDMCTPGCNE EGFGYLMSPR EESAREYLLS ASRVLQAEEL HEKALDPFLL
       310        320        330        340        350        360
QAEFFEIPMN FVDPKEYDIP GLVRKNRYKT ILPNPHSRVC LTSPDPDDPL SSYINANYIR
       370        380        390        400        410        420
GYGGEEKVYI ATQGPIVSTV ADFWRMVWQE HTPIIVMITN IEEMNEKCTE YWPEEQVAYD
       430        440        450        460        470        480
GVEITVQKVI HTEDYRLRLI SLKSGTEERG LKHYWFTSWP DQKTPDRAPP LLHLVREVEE
       490        500        510        520        530        540
AAQQEGPHCA PIIVHCSAGI GRTGCFIATS ICCQQLRQEG VVDILKTTCQ LRQDRGGMIQ
       550        560
TCEQYQFVHH VMSLYEKQLS HQSPE         10         20         30         40         50         60
MNYEGARSER ENHAADDSEG GALDMCCSER LPGLPQPIVM EALDEAEGLQ DSQREMPPPP
        70         80         90        100        110        120
PPSPPSDPAQ KPPPRGAGSH SLTVRSSLCL FAASQFLLAC GVLWFSGYGH IWSQNATNLV
       130        140        150        160        170        180
SSLLTLLKQL EPTAWLDSGT WGVPSLLLVF LSVGLVLVTT LVWHLLRTPP EPPTPLPPED
       190        200        210        220        230        240
RRQSVSRQPS FTYSEWMEEK IEDDFLDLDP VPETPVFDCV MDIKPEADPT SLTVKSMGLQ
       250        260        270        280        290        300
ERRGSNVSLT LDMCTPGCNE EGFGYLMSPR EESAREYLLS ASRVLQAEEL HEKALDPFLL
       310        320        330        340        350        360
QAEFFEIPMN FVDPKEYDIP GLVRKNRYKT ILPNPHSRVC LTSPDPDDPL SSYINANYIR
       370        380        390        400        410        420
GYGGEEKVYI ATQGPIVSTV ADFWRMVWQE HTPIIVMITN IEEMNEKCTE YWPEEQVAYD
       430        440        450        460        470        480
GVEITVQKVI HTEDYRLRLI SLKSGTEERG LKHYWFTSWP DQKTPDRAPP LLHLVREVEE
       490        500        510        520        530        540
AAQQEGPHCA PIIVHCSAGI GRTGCFIATS ICCQQLRQEG VVDILKTTCQ LRQDRGGMIQ
       550        560
TCEQYQFVHH VMSLYEKQLS HQSPE

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P54829-1-unknown	MNYEGA...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P54829-1-unknown	MNYEGA...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86524
P54829-25-unknown	MCCSER...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt86525
P54829-25-unknown	MCCSER...	25	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000379471
P54829-25-unknown	MCCSER...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt109911
P54829-197-unknown	MEEKIE...	197	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000435056
P54829-197-unknown	MEEKIE...	197	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198023
P54829-197-unknown	MEEKIE...	197	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198022

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HQSPE	565	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HQSPE	565	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82142
...HQSPE	565	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt82143

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)