TopFIND 4.0

P54869: Hydroxymethylglutaryl-CoA synthase, mitochondrial

General Information

Protein names
- Hydroxymethylglutaryl-CoA synthase, mitochondrial
- HMG-CoA synthase
- 2.3.3.10 {ECO:0000269|PubMed:24315375}
- 3-hydroxy-3-methylglutaryl coenzyme A synthase
Gene names Hmgcs2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P54869

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MQRLLAPARR VLQVKRAMQE TSLTPAHLLS AAQQRFSTIP PAPLAKTDTW PKDVGILALE 
        70         80         90        100        110        120 
VYFPAQYVDQ TDLEKFNNVE AGKYTVGLGQ TRMGFCSVQE DINSLCLTVV QRLMERTKLP 
       130        140        150        160        170        180 
WDAVGRLEVG TETIIDKSKA VKTVLMELFQ DSGNTDIEGI DTTNACYGGT ASLFNAANWM 
       190        200        210        220        230        240 
ESSYWDGRYA LVVCGDIAVY PSGNARPTGG AGAVAMLIGP KAPLVLEQGL RGTHMENAYD 
       250        260        270        280        290        300 
FYKPNLASEY PLVDGKLSIQ CYLRALDRCY AAYRKKIQNQ WKQAGNNQPF TLDDVQYMIF 
       310        320        330        340        350        360 
HTPFCKMVQK SLARLMFNDF LSSSSDKQNN LYKGLEAFRG LKLEETYTNK DVDKALLKAS 
       370        380        390        400        410        420 
LDMFNQKTKA SLYLSTNNGN MYTSSLYGCL ASLLSHHSAQ ELAGSRIGAF SYGSGLAASF 
       430        440        450        460        470        480 
FSFRVSKDAS PGSPLEKLVS SVSDLPKRLD SRRRMSPEEF TEIMNQREQF YHKVNFSPPG 
       490        500    
DTSNLFPGTW YLERVDEMHR RKYARCPV

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P54869-38-unknown TIPPAP... 38 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ARCPV 508 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)