TopFIND 4.0

P54873: Hydroxymethylglutaryl-CoA synthase

General Information

Protein names
- Hydroxymethylglutaryl-CoA synthase
- HMG-CoA synthase
- 2.3.3.10
- 3-hydroxy-3-methylglutaryl coenzyme A synthase
- Protein EMBRYO DEFECTIVE 2778
- Protein FLAKY POLLEN 1
Gene names HMGS
Organism Arabidopsis thaliana
Protease Family
Protease ID
Chromosome location
UniProt ID P54873

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAKNVGILAM DIYFPPTCVQ QEALEAHDGA SKGKYTIGLG QDCLAFCTEL EDVISMSFNA 
        70         80         90        100        110        120 
VTSLFEKYKI DPNQIGRLEV GSETVIDKSK SIKTFLMQLF EKCGNTDVEG VDSTNACYGG 
       130        140        150        160        170        180 
TAALLNCVNW VESNSWDGRY GLVICTDSAV YAEGPARPTG GAAAIAMLIG PDAPIVFESK 
       190        200        210        220        230        240 
LRASHMAHVY DFYKPNLASE YPVVDGKLSQ TCYLMALDSC YKHLCNKFEK IEGKEFSIND 
       250        260        270        280        290        300 
ADYIVFHSPY NKLVQKSFAR LLYNDFLRNA SSIDEAAKEK FTPYSSLTLD ESYQSRDLEK 
       310        320        330        340        350        360 
VSQQIAKPFY DAKVQPTTLI PKEVGNMYTA SLYAAFASLI HKKHNDLAGK RVVMFSYGSG 
       370        380        390        400        410        420 
STATMFSLRL NDNKPPFSIS NIASVMDVGG KLKARHEYAP EKFVETMKLM EHRYGAKDFV 
       430        440        450        460    
TTKEGIIDLL APGTYYLKEV DSLYRRFYGK KGEDGSVANG H

Isoforms

- Isoform 2 of Hydroxymethylglutaryl-CoA synthase

Sequence View

        10         20         30         40         50         60 
MAKNVGILAM DIYFPPTCVQ QEALEAHDGA SKGKYTIGLG QDCLAFCTEL EDVISMSFNA 
        70         80         90        100        110        120 
VTSLFEKYKI DPNQIGRLEV GSETVIDKSK SIKTFLMQLF EKCGNTDVEG VDSTNACYGG 
       130        140        150        160        170        180 
TAALLNCVNW VESNSWDGRY GLVICTDSAV YAEGPARPTG GAAAIAMLIG PDAPIVFESK 
       190        200        210        220        230        240 
LRASHMAHVY DFYKPNLASE YPVVDGKLSQ TCYLMALDSC YKHLCNKFEK IEGKEFSIND 
       250        260        270        280        290        300 
ADYIVFHSPY NKLVQKSFAR LLYNDFLRNA SSIDEAAKEK FTPYSSLTLD ESYQSRDLEK 
       310        320        330        340        350        360 
VSQQIAKPFY DAKVQPTTLI PKEVGNMYTA SLYAAFASLI HKKHNDLAGK RVVMFSYGSG 
       370        380        390        400        410        420 
STATMFSLRL NDNKPPFSIS NIASVMDVGG KLKARHEYAP EKFVETMKLM EHRYGAKDFV 
       430        440        450        460    
TTKEGIIDLL APGTYYLKEV DSLYRRFYGK KGEDGSVANG H



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P54873-1-unknown MAKNVG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P54873-56-unknown MSFNAV... 56 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77071

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VANGH 461 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...VANGH 461 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt72689

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)