P55039: Developmentally-regulated GTP-binding protein 2

General Information

Protein names	- Developmentally-regulated GTP-binding protein 2 - DRG-2 - Translation factor GTPase DRG2 - TRAFAC GTPase DRG2 - 3.6.5.- {ECO:0000305\|PubMed:29915238}
Gene names	DRG2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P55039

5 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGILEKISEI EKEIARTQKN KATEYHLGLL KAKLAKYRAQ LLEPSKSASS KGEGFDVMKS
        70         80         90        100        110        120
GDARVALIGF PSVGKSTFLS LMTSTASEAA SYEFTTLTCI PGVIEYKGAN IQLLDLPGII
       130        140        150        160        170        180
EGAAQGKGRG RQVIAVARTA DVIIMMLDAT KGEVQRSLLE KELESVGIRL NKHKPNIYFK
       190        200        210        220        230        240
PKKGGGISFN STVTLTQCSE KLVQLILHEY KIFNAEVLFR EDCSPDEFID VIVGNRVYMP
       250        260        270        280        290        300
CLYVYNKIDQ ISMEEVDRLA RKPNSVVISC GMKLNLDYLL EMLWEYLALT CIYTKKRGQR
       310        320        330        340        350        360
PDFTDAIILR KGASVEHVCH RIHRSLASQF KYALVWGTST KYSPQRVGLT HTMEHEDVIQ

IVKK

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

5 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P55039-1-unknown	MGILEK...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P55039-2-	GILEKI...	2		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352
P55039-2-unknown	GILEKI...	2		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P55039-2-unknown	GILEKI...	2		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P55039-39-unknown	AQLLEP...	39		unknown			Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage...	18722006
P55039-39-	AQLLEP...	39		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_Etoposide	23264352
P55039-39-	AQLLEP...	39		Subtiligase Based Positive Selection		Wells	Jurkat_untreated	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...RQVIAV	135	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000464076
...NAEVLF	218	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000462060
...QIVKK	364	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)