P55055: Oxysterols receptor LXR-beta

General Information

Protein names	- Oxysterols receptor LXR-beta - Liver X receptor beta - Nuclear receptor NER - Nuclear receptor subfamily 1 group H member 2 - Ubiquitously-expressed nuclear receptor
Gene names	NR1H2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P55055

3 N-termini

5 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSSPTTSSLD TPLPGNGPPQ PGAPSSSPTV KEEGPEPWPG GPDPDVPGTD EASSACSTDW
        70         80         90        100        110        120
VIPDPEEEPE RKRKKGPAPK MLGHELCRVC GDKASGFHYN VLSCEGCKGF FRRSVVRGGA
       130        140        150        160        170        180
RRYACRGGGT CQMDAFMRRK CQQCRLRKCK EAGMREQCVL SEEQIRKKKI RKQQQESQSQ
       190        200        210        220        230        240
SQSPVGPQGS SSSASGPGAS PGGSEAGSQG SGEGEGVQLT AAQELMIQQL VAAQLQCNKR
       250        260        270        280        290        300
SFSDQPKVTP WPLGADPQSR DARQQRFAHF TELAIISVQE IVDFAKQVPG FLQLGREDQI
       310        320        330        340        350        360
ALLKASTIEI MLLETARRYN HETECITFLK DFTYSKDDFH RAGLQVEFIN PIFEFSRAMR
       370        380        390        400        410        420
RLGLDDAEYA LLIAINIFSA DRPNVQEPGR VEALQQPYVE ALLSYTRIKR PQDQLRFPRM
       430        440        450        460
LMKLVSLRTL SSVHSEQVFA LRLQDKKLPP LLSEIWDVHE

Isoforms

- Isoform 2 of Oxysterols receptor LXR-beta

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 5 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P55055-1-unknown	MSSPTT...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P55055-1-unknown	MSSPTT...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt83179
P55055-60-	WVIPDP...	60		Subtiligase Based Positive Selection		Wells	apoptotic_MM1s_bort	23264352
P55055-226-unknown	MIQQLV...	226	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000445074
P55055-226-unknown	MIQQLV...	226	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt129664

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...EPWPGG	40	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000473099
...EPWPGG	40	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt108093
...FRRSVV	115	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000470518
...EAGSQG	209	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000472138
...EAGSQG	209	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt108096
...ELMIQQ	228	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000469778
...ELMIQQ	228	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt108098
...WDVHE	460	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...WDVHE	460	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt78797

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)