TopFIND 4.0

P55215: Caspase-2

General Information

Protein names
- Caspase-2
- CASP-2
- 3.4.22.55
- Protease ICH-1
- Caspase-2 subunit p18
- Caspase-2 subunit p13
- Caspase-2 subunit p12
Gene names Casp2
Organism Rattus norvegicus
Protease Family
Protease ID C14.006
Chromosome location
UniProt ID P55215

5

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAASSGRSQS SLHRKGLMAA DRRSRILAVC GMHPDHQETL KKNRVVLAKQ LLLSELLEHL 
        70         80         90        100        110        120 
LEKDIITLEM RELIQAKGGS FSQNVELLNL LPKRGPQAFD AFCEALRETR QGHLEDLLLT 
       130        140        150        160        170        180 
TLSDIQHILP PLSCDYDSSL PFSVCESCPP HKQSRLSTDT MEHSLDNGDG PPCLQVKPCT 
       190        200        210        220        230        240 
PEFYQAHYQL AYRLQSQPRG LALVMSNVHF TGEKDLEFRS GGDVDHTTLV TLFKLLGYNV 
       250        260        270        280        290        300 
HVLYDQTAQE MQEKLQNFAQ LPAHRVTDSC IVALLSHGVE GGIYGVDGKL LQLQEVFRLF 
       310        320        330        340        350        360 
DNANCPSLQN KPKMFFIQAC RGDETDRGVD QQDGKNHAQS PGCEESDAGK EELMKMRLPT 
       370        380        390        400        410        420 
RSDMICGYAC LKGNAAMRNT KRGSWYIEAL TQVFSERACD MHVADMLVKV NALIKEREGY 
       430        440        450    
APGTEFHRCK EMSEYCSTLC QQLYLFPGYP PT

Isoforms

- Isoform 2 of Caspase-2

Sequence View

        10         20         30         40         50         60 
MAASSGRSQS SLHRKGLMAA DRRSRILAVC GMHPDHQETL KKNRVVLAKQ LLLSELLEHL 
        70         80         90        100        110        120 
LEKDIITLEM RELIQAKGGS FSQNVELLNL LPKRGPQAFD AFCEALRETR QGHLEDLLLT 
       130        140        150        160        170        180 
TLSDIQHILP PLSCDYDSSL PFSVCESCPP HKQSRLSTDT MEHSLDNGDG PPCLQVKPCT 
       190        200        210        220        230        240 
PEFYQAHYQL AYRLQSQPRG LALVMSNVHF TGEKDLEFRS GGDVDHTTLV TLFKLLGYNV 
       250        260        270        280        290        300 
HVLYDQTAQE MQEKLQNFAQ LPAHRVTDSC IVALLSHGVE GGIYGVDGKL LQLQEVFRLF 
       310        320        330        340        350        360 
DNANCPSLQN KPKMFFIQAC RGDETDRGVD QQDGKNHAQS PGCEESDAGK EELMKMRLPT 
       370        380        390        400        410        420 
RSDMICGYAC LKGNAAMRNT KRGSWYIEAL TQVFSERACD MHVADMLVKV NALIKEREGY 
       430        440        450    
APGTEFHRCK EMSEYCSTLC QQLYLFPGYP PT



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

5 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RGDETD 325 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...GYPPT 452 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)