P55290: Cadherin-13

General Information

Protein names	- Cadherin-13 - Heart cadherin - H-cadherin - P105 - Truncated cadherin - T-cad - T-cadherin
Gene names	CDH13
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P55290

3 N-termini

3 C-termini

1 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Cadherin-13 - Isoform 3 of Cadherin-13 - Isoform 4 of Cadherin-13 - Isoform 5 of Cadherin-13

Sequence View

        10         20         30         40         50         60
MQPRTPLVLC VLLSQVLLLT SAEDLDCTPG FQQKVFHINQ PAEFIEDQSI LNLTFSDCKG
        70         80         90        100        110        120
NDKLRYEVSS PYFKVNSDGG LVALRNITAV GKTLFVHART PHAEDMAELV IVGGKDIQGS
       130        140        150        160        170        180
LQDIFKFART SPVPRQKRSI VVSPILIPEN QRQPFPRDVG KVVDSDRPER SKFRLTGKGV
       190        200        210        220        230        240
DQEPKGIFRI NENTGSVSVT RTLDREVIAV YQLFVETTDV NGKTLEGPVP LEVIVIDQND
       250        260        270        280        290        300
NRPIFREGPY IGHVMEGSPT GTTVMRMTAF DADDPATDNA LLRYNIRQQT PDKPSPNMFY
       310        320        330        340        350        360
IDPEKGDIVT VVSPALLDRE TLENPKYELI IEAQDMAGLD VGLTGTATAT IMIDDKNDHS
       370        380        390        400        410        420
PKFTKKEFQA TVEEGAVGVI VNLTVEDKDD PTTGAWRAAY TIINGNPGQS FEIHTNPQTN
       430        440        450        460        470        480
EGMLSVVKPL DYEISAFHTL LIKVENEDPL VPDVSYGPSS TATVHITVLD VNEGPVFYPD
       490        500        510        520        530        540
PMMVTRQEDL SVGSVLLTVN ATDPDSLQHQ TIRYSVYKDP AGWLNINPIN GTVDTTAVLD
       550        560        570        580        590        600
RESPFVDNSV YTALFLAIDS GNPPATGTGT LLITLEDVND NAPFIYPTVA EVCDDAKNLS
       610        620        630        640        650        660
VVILGASDKD LHPNTDPFKF EIHKQAVPDK VWKISKINNT HALVSLLQNL NKANYNLPIM
       670        680        690        700        710
VTDSGKPPMT NITDLRVQVC SCRNSKVDCN AAGALRFSLP SVLLLSLFSL ACL         10         20         30         40         50         60
MQPRTPLVLC VLLSQVLLLT SAEDLDCTPG FQQKVFHINQ PAEFIEDQSI LNLTFSDCKG
        70         80         90        100        110        120
NDKLRYEVSS PYFKVNSDGG LVALRNITAV GKTLFVHART PHAEDMAELV IVGGKDIQGS
       130        140        150        160        170        180
LQDIFKFART SPVPRQKRSI VVSPILIPEN QRQPFPRDVG KVVDSDRPER SKFRLTGKGV
       190        200        210        220        230        240
DQEPKGIFRI NENTGSVSVT RTLDREVIAV YQLFVETTDV NGKTLEGPVP LEVIVIDQND
       250        260        270        280        290        300
NRPIFREGPY IGHVMEGSPT GTTVMRMTAF DADDPATDNA LLRYNIRQQT PDKPSPNMFY
       310        320        330        340        350        360
IDPEKGDIVT VVSPALLDRE TLENPKYELI IEAQDMAGLD VGLTGTATAT IMIDDKNDHS
       370        380        390        400        410        420
PKFTKKEFQA TVEEGAVGVI VNLTVEDKDD PTTGAWRAAY TIINGNPGQS FEIHTNPQTN
       430        440        450        460        470        480
EGMLSVVKPL DYEISAFHTL LIKVENEDPL VPDVSYGPSS TATVHITVLD VNEGPVFYPD
       490        500        510        520        530        540
PMMVTRQEDL SVGSVLLTVN ATDPDSLQHQ TIRYSVYKDP AGWLNINPIN GTVDTTAVLD
       550        560        570        580        590        600
RESPFVDNSV YTALFLAIDS GNPPATGTGT LLITLEDVND NAPFIYPTVA EVCDDAKNLS
       610        620        630        640        650        660
VVILGASDKD LHPNTDPFKF EIHKQAVPDK VWKISKINNT HALVSLLQNL NKANYNLPIM
       670        680        690        700        710
VTDSGKPPMT NITDLRVQVC SCRNSKVDCN AAGALRFSLP SVLLLSLFSL ACL         10         20         30         40         50         60
MQPRTPLVLC VLLSQVLLLT SAEDLDCTPG FQQKVFHINQ PAEFIEDQSI LNLTFSDCKG
        70         80         90        100        110        120
NDKLRYEVSS PYFKVNSDGG LVALRNITAV GKTLFVHART PHAEDMAELV IVGGKDIQGS
       130        140        150        160        170        180
LQDIFKFART SPVPRQKRSI VVSPILIPEN QRQPFPRDVG KVVDSDRPER SKFRLTGKGV
       190        200        210        220        230        240
DQEPKGIFRI NENTGSVSVT RTLDREVIAV YQLFVETTDV NGKTLEGPVP LEVIVIDQND
       250        260        270        280        290        300
NRPIFREGPY IGHVMEGSPT GTTVMRMTAF DADDPATDNA LLRYNIRQQT PDKPSPNMFY
       310        320        330        340        350        360
IDPEKGDIVT VVSPALLDRE TLENPKYELI IEAQDMAGLD VGLTGTATAT IMIDDKNDHS
       370        380        390        400        410        420
PKFTKKEFQA TVEEGAVGVI VNLTVEDKDD PTTGAWRAAY TIINGNPGQS FEIHTNPQTN
       430        440        450        460        470        480
EGMLSVVKPL DYEISAFHTL LIKVENEDPL VPDVSYGPSS TATVHITVLD VNEGPVFYPD
       490        500        510        520        530        540
PMMVTRQEDL SVGSVLLTVN ATDPDSLQHQ TIRYSVYKDP AGWLNINPIN GTVDTTAVLD
       550        560        570        580        590        600
RESPFVDNSV YTALFLAIDS GNPPATGTGT LLITLEDVND NAPFIYPTVA EVCDDAKNLS
       610        620        630        640        650        660
VVILGASDKD LHPNTDPFKF EIHKQAVPDK VWKISKINNT HALVSLLQNL NKANYNLPIM
       670        680        690        700        710
VTDSGKPPMT NITDLRVQVC SCRNSKVDCN AAGALRFSLP SVLLLSLFSL ACL         10         20         30         40         50         60
MQPRTPLVLC VLLSQVLLLT SAEDLDCTPG FQQKVFHINQ PAEFIEDQSI LNLTFSDCKG
        70         80         90        100        110        120
NDKLRYEVSS PYFKVNSDGG LVALRNITAV GKTLFVHART PHAEDMAELV IVGGKDIQGS
       130        140        150        160        170        180
LQDIFKFART SPVPRQKRSI VVSPILIPEN QRQPFPRDVG KVVDSDRPER SKFRLTGKGV
       190        200        210        220        230        240
DQEPKGIFRI NENTGSVSVT RTLDREVIAV YQLFVETTDV NGKTLEGPVP LEVIVIDQND
       250        260        270        280        290        300
NRPIFREGPY IGHVMEGSPT GTTVMRMTAF DADDPATDNA LLRYNIRQQT PDKPSPNMFY
       310        320        330        340        350        360
IDPEKGDIVT VVSPALLDRE TLENPKYELI IEAQDMAGLD VGLTGTATAT IMIDDKNDHS
       370        380        390        400        410        420
PKFTKKEFQA TVEEGAVGVI VNLTVEDKDD PTTGAWRAAY TIINGNPGQS FEIHTNPQTN
       430        440        450        460        470        480
EGMLSVVKPL DYEISAFHTL LIKVENEDPL VPDVSYGPSS TATVHITVLD VNEGPVFYPD
       490        500        510        520        530        540
PMMVTRQEDL SVGSVLLTVN ATDPDSLQHQ TIRYSVYKDP AGWLNINPIN GTVDTTAVLD
       550        560        570        580        590        600
RESPFVDNSV YTALFLAIDS GNPPATGTGT LLITLEDVND NAPFIYPTVA EVCDDAKNLS
       610        620        630        640        650        660
VVILGASDKD LHPNTDPFKF EIHKQAVPDK VWKISKINNT HALVSLLQNL NKANYNLPIM
       670        680        690        700        710
VTDSGKPPMT NITDLRVQVC SCRNSKVDCN AAGALRFSLP SVLLLSLFSL ACL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 3 C-termini - 1 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P55290-1-unknown	MQPRTP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt69120
P55290-1-unknown	MQPRTP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt69122
P55290-1-unknown	MQPRTP...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt69119
P55290-23-unknown	EDLDCT...	23	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P55290-23-unknown	EDLDCT...	23	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113359
P55290-23-unknown	EDLDCT...	23	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113361
P55290-23-unknown	EDLDCT...	23	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113362
P55290-23-unknown	EDLDCT...	23	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113360
P55290-139-unknown	SIVVSP...	139	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P55290-139-unknown	SIVVSP...	139	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16357
P55290-139-unknown	SIVVSP...	139	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt115942
P55290-139-unknown	SIVVSP...	139	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt115943
P55290-139-unknown	SIVVSP...	139	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt115941

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PRQKRS	138	inferred from cleavage	unknown	TopFIND	Inferred from cleavage TC16357
...PRQKRS	138	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127525
...PRQKRS	138	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt127527
...PRQKRS	138	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt129417
...CNAAGA	693	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...CNAAGA	693	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt93256
...CNAAGA	693	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt93257
...SLACL	713	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt64740
...SLACL	713	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt64739

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
KLK4_HUMAN	138	QKRS.\|.SIVV	inferred from experiment	unknown	MEROPS	Nelson PS	Matsumura M et al.:Substrates of the prostate-spec... (S01.251)	15389820,

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)