TopFIND 4.0

P56159: GDNF family receptor alpha-1

General Information

Protein names
- GDNF family receptor alpha-1
- GDNF receptor alpha-1
- GDNFR-alpha-1
- GFR-alpha-1
- RET ligand 1
- TGF-beta-related neurotrophic factor receptor 1
Gene names GFRA1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P56159

2

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFLATLYFAL PLLDLLLSAE VSGGDRLDCV KASDQCLKEQ SCSTKYRTLR QCVAGKETNF 
        70         80         90        100        110        120 
SLASGLEAKD ECRSAMEALK QKSLYNCRCK RGMKKEKNCL RIYWSMYQSL QGNDLLEDSP 
       130        140        150        160        170        180 
YEPVNSRLSD IFRVVPFISD VFQQVEHIPK GNNCLDAAKA CNLDDICKKY RSAYITPCTT 
       190        200        210        220        230        240 
SVSNDVCNRR KCHKALRQFF DKVPAKHSYG MLFCSCRDIA CTERRRQTIV PVCSYEEREK 
       250        260        270        280        290        300 
PNCLNLQDSC KTNYICRSRL ADFFTNCQPE SRSVSSCLKE NYADCLLAYS GLIGTVMTPN 
       310        320        330        340        350        360 
YIDSSSLSVA PWCDCSNSGN DLEECLKFLN FFKDNTCLKN AIQAFGNGSD VTVWQPAFPV 
       370        380        390        400        410        420 
QTTTATTTTA LRVKNKPLGP AGSENEIPTH VLPPCANLQA QKLKSNVSGN THLCISNGNY 
       430        440        450        460    
EKEGLGASSH ITTKSMAAPP SCGLSPLLVL VVTALSTLLS LTETS

Isoforms

- Isoform 2 of GDNF family receptor alpha-1

Sequence View

        10         20         30         40         50         60 
MFLATLYFAL PLLDLLLSAE VSGGDRLDCV KASDQCLKEQ SCSTKYRTLR QCVAGKETNF 
        70         80         90        100        110        120 
SLASGLEAKD ECRSAMEALK QKSLYNCRCK RGMKKEKNCL RIYWSMYQSL QGNDLLEDSP 
       130        140        150        160        170        180 
YEPVNSRLSD IFRVVPFISD VFQQVEHIPK GNNCLDAAKA CNLDDICKKY RSAYITPCTT 
       190        200        210        220        230        240 
SVSNDVCNRR KCHKALRQFF DKVPAKHSYG MLFCSCRDIA CTERRRQTIV PVCSYEEREK 
       250        260        270        280        290        300 
PNCLNLQDSC KTNYICRSRL ADFFTNCQPE SRSVSSCLKE NYADCLLAYS GLIGTVMTPN 
       310        320        330        340        350        360 
YIDSSSLSVA PWCDCSNSGN DLEECLKFLN FFKDNTCLKN AIQAFGNGSD VTVWQPAFPV 
       370        380        390        400        410        420 
QTTTATTTTA LRVKNKPLGP AGSENEIPTH VLPPCANLQA QKLKSNVSGN THLCISNGNY 
       430        440        450        460    
EKEGLGASSH ITTKSMAAPP SCGLSPLLVL VVTALSTLLS LTETS



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Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P56159-1-unknown MFLATL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt75900
    P56159-25-unknown DRLDCV... 25 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P56159-25-unknown DRLDCV... 25 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113742

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)