TopFIND 4.0

P56720: Sterol regulatory element-binding protein 1

General Information

Protein names
- Sterol regulatory element-binding protein 1
- SREBP-1
- Adipocyte determination- and differentiation-dependent factor 1
- ADD1
- Sterol regulatory element-binding transcription factor 1
- Processed sterol regulatory element-binding protein 1
Gene names Srebf1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P56720

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MDELPFGEAA LEQALAEVCE MDAALLTDIE DMLQLINNQD SDFPGLFDAP YAGGETGDTG 
        70         80         90        100        110        120 
PSSPGASSPE SFSSPASLGS SLEAFLGGPK VTPAPLSPPP SAPTAVKMYP SVPPFSPGPG 
       130        140        150        160        170        180 
IKEEPVPLTI LQPPAPQPSP GTLLPPSFPP PPVQLSPAPV LGYSSLPSGF SGTLPGNTQQ 
       190        200        210        220        230        240 
TPSSLPLGST PGISPTPLHT QVQSSAAQQP PPASAAPRMS TVASQIQQVP VVLQPHFIKA 
       250        260        270        280        290        300 
DSLLLTAVKT DTGATMKTAG INTLAPGTAV QAGPLQTLVS GGTILATVPL VVDTDKLPIH 
       310        320        330        340        350        360 
RLAAGGKALG SAQSRGEKRT AHNAIEKRYR SSINDKIVEL KDLVVGTEAK LNKSAVLRKA 
       370        380        390        400        410        420 
IDYIRFLQHS NQKLKQENLT LRSAHKSKSL KDLVSACGSG GGTDVSMEGM KPEVVETLTP 
       430        440        450        460        470        480 
PPSDAGSPSQ SSPLSLGSRG SSSGGSDSEP DSPAFEDNQV KAQRLPSHSR GMLDRSRLAL 
       490        500        510        520        530        540 
CVLVFLCLTC NPLASLFGWG ILTPSDASGV HRSSGRSMLE AESRDGSNWT QWLLPPLVWL 
       550        560        570        580        590        600 
ANGLLVLACL ALLFVYGEPV TRPHSGPAVH FWRHRKQADL DLARGDFAQA AQQLWLALQA 
       610        620        630        640        650        660 
LGRPLPTSNL DLACSLLWNL VRHLLQRLWV GRWLAGQAGG LQRDYRLRKD ARASARDAAV 
       670        680        690        700        710        720 
VYHKLHQLHA MGKYTGGHLV ASNLALSALN LAECAGDAIS MATLAEIYVA AALRVKTSLP 
       730        740        750        760        770        780 
RALHFLTRFF LSSARQACLA QSGAVPLAMQ WLCHPVGHRF FVDGDWAVHG APQESLYSVA 
       790        800        810        820        830        840 
GNPVDPLAQV TRLFCEHLLE RALNCIAQPS PGAADGDREF SDALGYLQLL NSCSDAVGAP 
       850        860        870        880        890        900 
ACSFSVSSSM ATTTGTDPVA KWWASLTAVV IHWLRRDEEA AERLYPLVEH IPQVLQETER 
       910        920        930        940        950        960 
PLPRAALYSF KAARALLDHR KVESSPASLA ICEKASGYLR DSLASTSTAS SIDKAMQLLL 
       970        980        990       1000       1010       1020 
CDLLLVARTS LWRRQQSAAS AQGAHGTSNG PQASALELRG FQHDLSSLRR LAQSFRPAMR 
      1030       1040       1050       1060       1070       1080 
RVFLHEATAR LMAGASPART HQLLDRSLRR RAGSSGKGGA AAELEPRPTW REHTEALLLA 
      1090       1100       1110       1120       1130    
SCYLPPAFLS APGQRVSMLA EAARTVEKLG DHRLLLDCQQ MLLRLGGGTT VTSS

Isoforms

- Isoform SREBP-1C of Sterol regulatory element-binding protein 1

Sequence View

        10         20         30         40         50         60 
MDELPFGEAA LEQALAEVCE MDAALLTDIE DMLQLINNQD SDFPGLFDAP YAGGETGDTG 
        70         80         90        100        110        120 
PSSPGASSPE SFSSPASLGS SLEAFLGGPK VTPAPLSPPP SAPTAVKMYP SVPPFSPGPG 
       130        140        150        160        170        180 
IKEEPVPLTI LQPPAPQPSP GTLLPPSFPP PPVQLSPAPV LGYSSLPSGF SGTLPGNTQQ 
       190        200        210        220        230        240 
TPSSLPLGST PGISPTPLHT QVQSSAAQQP PPASAAPRMS TVASQIQQVP VVLQPHFIKA 
       250        260        270        280        290        300 
DSLLLTAVKT DTGATMKTAG INTLAPGTAV QAGPLQTLVS GGTILATVPL VVDTDKLPIH 
       310        320        330        340        350        360 
RLAAGGKALG SAQSRGEKRT AHNAIEKRYR SSINDKIVEL KDLVVGTEAK LNKSAVLRKA 
       370        380        390        400        410        420 
IDYIRFLQHS NQKLKQENLT LRSAHKSKSL KDLVSACGSG GGTDVSMEGM KPEVVETLTP 
       430        440        450        460        470        480 
PPSDAGSPSQ SSPLSLGSRG SSSGGSDSEP DSPAFEDNQV KAQRLPSHSR GMLDRSRLAL 
       490        500        510        520        530        540 
CVLVFLCLTC NPLASLFGWG ILTPSDASGV HRSSGRSMLE AESRDGSNWT QWLLPPLVWL 
       550        560        570        580        590        600 
ANGLLVLACL ALLFVYGEPV TRPHSGPAVH FWRHRKQADL DLARGDFAQA AQQLWLALQA 
       610        620        630        640        650        660 
LGRPLPTSNL DLACSLLWNL VRHLLQRLWV GRWLAGQAGG LQRDYRLRKD ARASARDAAV 
       670        680        690        700        710        720 
VYHKLHQLHA MGKYTGGHLV ASNLALSALN LAECAGDAIS MATLAEIYVA AALRVKTSLP 
       730        740        750        760        770        780 
RALHFLTRFF LSSARQACLA QSGAVPLAMQ WLCHPVGHRF FVDGDWAVHG APQESLYSVA 
       790        800        810        820        830        840 
GNPVDPLAQV TRLFCEHLLE RALNCIAQPS PGAADGDREF SDALGYLQLL NSCSDAVGAP 
       850        860        870        880        890        900 
ACSFSVSSSM ATTTGTDPVA KWWASLTAVV IHWLRRDEEA AERLYPLVEH IPQVLQETER 
       910        920        930        940        950        960 
PLPRAALYSF KAARALLDHR KVESSPASLA ICEKASGYLR DSLASTSTAS SIDKAMQLLL 
       970        980        990       1000       1010       1020 
CDLLLVARTS LWRRQQSAAS AQGAHGTSNG PQASALELRG FQHDLSSLRR LAQSFRPAMR 
      1030       1040       1050       1060       1070       1080 
RVFLHEATAR LMAGASPART HQLLDRSLRR RAGSSGKGGA AAELEPRPTW REHTEALLLA 
      1090       1100       1110       1120       1130    
SCYLPPAFLS APGQRVSMLA EAARTVEKLG DHRLLLDCQQ MLLRLGGGTT VTSS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P56720-1-unknown MDELPF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SRLALC 480 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...TVTSS 1134 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)