TopFIND 4.0

P57790: Kelch-like ECH-associated protein 1

General Information

Protein names
- Kelch-like ECH-associated protein 1
- Cytosolic inhibitor of Nrf2
- INrf2
Gene names Keap1
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID P57790

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MQPEPKPSGA PRSSQFLPLW SKCPEGAGDA VMYASTECKA EVTPSQDGNR TFSYTLEDHT 
        70         80         90        100        110        120 
KQAFGIMNEL RLSQQLCDVT LQVKYEDIPA AQFMAHKVVL ASSSPVFKAM FTNGLREQGM 
       130        140        150        160        170        180 
EVVSIEGIHP KVMERLIEFA YTASISVGEK CVLHVMNGAV MYQIDSVVRA CSDFLVQQLD 
       190        200        210        220        230        240 
PSNAIGIANF AEQIGCTELH QRAREYIYMH FGEVAKQEEF FNLSHCQLAT LISRDDLNVR 
       250        260        270        280        290        300 
CESEVFHACI DWVKYDCPQR RFYVQALLRA VRCHALTPRF LQTQLQKCEI LQADARCKDY 
       310        320        330        340        350        360 
LVQIFQELTL HKPTQAVPCR APKVGRLIYT AGGYFRQSLS YLEAYNPSNG SWLRLADLQV 
       370        380        390        400        410        420 
PRSGLAGCVV GGLLYAVGGR NNSPDGNTDS SALDCYNPMT NQWSPCASLS VPRNRSGGGV 
       430        440        450        460        470        480 
IDGHIYAVGG SHGCIHHSSV ERYEPDRDEW HLVAPMLTRR IGVGVAVLNR LLYAVGGFDG 
       490        500        510        520        530        540 
TNRLNSAECY YPERNEWRMI TPMNTIRSGA GVCVLHSCIY AAGGYDGQDQ LNSVERYDVE 
       550        560        570        580        590        600 
TETWTFVASM KHRRSALGIA VHQGRIYVLG GYDGHTFLDS VECYDPDTDT WSEVTRLTSG 
       610        620    
RSGVGVAVTM EPCRKQIDQQ NCTC

Isoforms



Sequence View



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P57790-1-unknown MQPEPK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QNCTC 624 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)