TopFIND 4.0

P58308: Orexin receptor type 2

General Information

Protein names
- Orexin receptor type 2
- Ox-2-R
- Ox2-R
- Ox2R
- Hypocretin receptor type 2
Gene names Hcrtr2
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P58308

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSSTKLEDSL SRRNWSSASE LNETQEPFLN PTDYDDEEFL RYLWREYLHP KEYEWVLIAG 
        70         80         90        100        110        120 
YIIVFVVALI GNVLVCVAVW KNHHMRTVTN YFIVNLSLAD VLVTITCLPA TLVVDITETW 
       130        140        150        160        170        180 
FFGQSLCKVI PYLQTVSVSV SVLTLSCIAL DRWYAICHPL MFKSTAKRAR NSIVVIWIVS 
       190        200        210        220        230        240 
CIIMIPQAIV MECSSMLPGL ANKTTLFTVC DEHWGGEVYP KMYHICFFLV TYMAPLCLMI 
       250        260        270        280        290        300 
LAYLQIFRKL WCRQIPGTSS VVQRKWKQQQ PVSQPRGSGQ QSKARISAVA AEIKQIRARR 
       310        320        330        340        350        360 
KTARMLMVVL LVFAICYLPI SILNVLKRVF GMFTHTEDRE TVYAWFTFSH WLVYANSAAN 
       370        380        390        400        410        420 
PIIYNFLSGK FREEFKAAFS CCLGVHHRQG DRLARGRTST ESRKSLTTQI SNFDNVSKLS 
       430        440        450        460    
EHVVLTSIST LPAANGAGPL QNWYLQQGVP SSLLSTWLEV 

Isoforms

- Isoform 2 of Orexin receptor type 2

Sequence View

        10         20         30         40         50         60 
MSSTKLEDSL SRRNWSSASE LNETQEPFLN PTDYDDEEFL RYLWREYLHP KEYEWVLIAG 
        70         80         90        100        110        120 
YIIVFVVALI GNVLVCVAVW KNHHMRTVTN YFIVNLSLAD VLVTITCLPA TLVVDITETW 
       130        140        150        160        170        180 
FFGQSLCKVI PYLQTVSVSV SVLTLSCIAL DRWYAICHPL MFKSTAKRAR NSIVVIWIVS 
       190        200        210        220        230        240 
CIIMIPQAIV MECSSMLPGL ANKTTLFTVC DEHWGGEVYP KMYHICFFLV TYMAPLCLMI 
       250        260        270        280        290        300 
LAYLQIFRKL WCRQIPGTSS VVQRKWKQQQ PVSQPRGSGQ QSKARISAVA AEIKQIRARR 
       310        320        330        340        350        360 
KTARMLMVVL LVFAICYLPI SILNVLKRVF GMFTHTEDRE TVYAWFTFSH WLVYANSAAN 
       370        380        390        400        410        420 
PIIYNFLSGK FREEFKAAFS CCLGVHHRQG DRLARGRTST ESRKSLTTQI SNFDNVSKLS 
       430        440        450        460    
EHVVLTSIST LPAANGAGPL QNWYLQQGVP SSLLSTWLEV 



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P58308-1-unknown MSSTKL... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P58308-1-unknown MSSTKL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt83935

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PLQNWY 443 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt79553
    ...TWLEV 460 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)