TopFIND 4.0

P58418: Clarin-1

General Information

Protein names
- Clarin-1
- Usher syndrome type-3 protein
Gene names CLRN1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P58418

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPSQQKKIIF CMAGVFSFAC ALGVVTALGT PLWIKATVLC KTGALLVNAS GQELDKFMGE 
        70         80         90        100        110        120 
MQYGLFHGEG VRQCGLGARP FRFSFFPDLL KAIPVSIHVN VILFSAILIV LTMVGTAFFM 
       130        140        150        160        170        180 
YNAFGKPFET LHGPLGLYLL SFISGSCGCL VMILFASEVK IHHLSEKIAN YKEGTYVYKT 
       190        200        210        220        230    
QSEKYTTSFW VIFFCFFVHF LNGLLIRLAG FQFPFAKSKD AETTNVAADL MY

Isoforms

- Isoform 2 of Clarin-1 - Isoform 3 of Clarin-1

Sequence View

        10         20         30         40         50         60 
MPSQQKKIIF CMAGVFSFAC ALGVVTALGT PLWIKATVLC KTGALLVNAS GQELDKFMGE 
        70         80         90        100        110        120 
MQYGLFHGEG VRQCGLGARP FRFSFFPDLL KAIPVSIHVN VILFSAILIV LTMVGTAFFM 
       130        140        150        160        170        180 
YNAFGKPFET LHGPLGLYLL SFISGSCGCL VMILFASEVK IHHLSEKIAN YKEGTYVYKT 
       190        200        210        220        230    
QSEKYTTSFW VIFFCFFVHF LNGLLIRLAG FQFPFAKSKD AETTNVAADL MY         10         20         30         40         50         60 
MPSQQKKIIF CMAGVFSFAC ALGVVTALGT PLWIKATVLC KTGALLVNAS GQELDKFMGE 
        70         80         90        100        110        120 
MQYGLFHGEG VRQCGLGARP FRFSFFPDLL KAIPVSIHVN VILFSAILIV LTMVGTAFFM 
       130        140        150        160        170        180 
YNAFGKPFET LHGPLGLYLL SFISGSCGCL VMILFASEVK IHHLSEKIAN YKEGTYVYKT 
       190        200        210        220        230    
QSEKYTTSFW VIFFCFFVHF LNGLLIRLAG FQFPFAKSKD AETTNVAADL MY



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P58418-1-unknown MPSQQK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P58418-1-unknown MPSQQK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt71021

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ADLMY 232 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ADLMY 232 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt66639

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)