TopFIND 4.0

P58753: Toll/interleukin-1 receptor domain-containing adapter protein

General Information

Protein names
- Toll/interleukin-1 receptor domain-containing adapter protein
- TIR domain-containing adapter protein
- Adaptor protein Wyatt
- MyD88 adapter-like protein
- MyD88-2
Gene names TIRAP
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID P58753

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASSTSLPAP GSRPKKPLGK MADWFRQTLL KKPKKRPNSP ESTSSDASQP TSQDSPLPPS 
        70         80         90        100        110        120 
LSSVTSPSLP PTHASDSGSS RWSKDYDVCV CHSEEDLVAA QDLVSYLEGS TASLRCFLQL 
       130        140        150        160        170        180 
RDATPGGAIV SELCQALSSS HCRVLLITPG FLQDPWCKYQ MLQALTEAPG AEGCTIPLLS 
       190        200        210        220    
GLSRAAYPPE LRFMYYVDGR GPDGGFRQVK EAVMRYLQTL S

Isoforms

- Isoform 2 of Toll/interleukin-1 receptor domain-containing adapter protein - Isoform 3 of Toll/interleukin-1 receptor domain-containing adapter protein

Sequence View

        10         20         30         40         50         60 
MASSTSLPAP GSRPKKPLGK MADWFRQTLL KKPKKRPNSP ESTSSDASQP TSQDSPLPPS 
        70         80         90        100        110        120 
LSSVTSPSLP PTHASDSGSS RWSKDYDVCV CHSEEDLVAA QDLVSYLEGS TASLRCFLQL 
       130        140        150        160        170        180 
RDATPGGAIV SELCQALSSS HCRVLLITPG FLQDPWCKYQ MLQALTEAPG AEGCTIPLLS 
       190        200        210        220    
GLSRAAYPPE LRFMYYVDGR GPDGGFRQVK EAVMRYLQTL S         10         20         30         40         50         60 
MASSTSLPAP GSRPKKPLGK MADWFRQTLL KKPKKRPNSP ESTSSDASQP TSQDSPLPPS 
        70         80         90        100        110        120 
LSSVTSPSLP PTHASDSGSS RWSKDYDVCV CHSEEDLVAA QDLVSYLEGS TASLRCFLQL 
       130        140        150        160        170        180 
RDATPGGAIV SELCQALSSS HCRVLLITPG FLQDPWCKYQ MLQALTEAPG AEGCTIPLLS 
       190        200        210        220    
GLSRAAYPPE LRFMYYVDGR GPDGGFRQVK EAVMRYLQTL S



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P58753-1-unknown MASSTS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P58753-1-unknown MASSTS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92195
    P58753-1-unknown MASSTS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt92196

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LQTLS 221 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)