P59941: NAD-dependent protein deacetylase sirtuin-6

General Information

Protein names	- NAD-dependent protein deacetylase sirtuin-6 - 3.5.1.- - Regulatory protein SIR2 homolog 6 - SIR2-like protein 6
Gene names	Sirt6
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P59941

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MSVNYAAGLS PYADKGKCGL PEIFDPPEEL ERKVWELARL MWQSSSVVFH TGAGISTASG
        70         80         90        100        110        120
IPDFRGPHGV WTMEERGLAP KFDTTFENAR PSKTHMALVQ LERMGFLSFL VSQNVDGLHV
       130        140        150        160        170        180
RSGFPRDKLA ELHGNMFVEE CPKCKTQYVR DTVVGTMGLK ATGRLCTVAK TRGLRACRGE
       190        200        210        220        230        240
LRDTILDWED SLPDRDLMLA DEASRTADLS VTLGTSLQIR PSGNLPLATK RRGGRLVIVN
       250        260        270        280        290        300
LQPTKHDRQA DLRIHGYVDE VMCRLMKHLG LEIPAWDGPC VLDKALPPLP RPVALKAEPP
       310        320        330
VHLNGAVHVS YKSKPNSPIL HRPPKRVKTE AAPS

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
P59941-2-unknown	MSVNYA...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P59941-2-unknown	MSVNYA...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P59941-2-Acetylation	SVNYAA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P59941-2-Acetylation	SVNYAA...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
P59941-41-unknown	MWQSSS...	41		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000113953
P59941-41-unknown	MWQSSS...	41		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118238

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...QLERMG	104	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSMUSP00000118238
	...EAAPS	334	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)