P60953: Cell division control protein 42 homolog {ECO:0000305}
| Protein names | - Cell division control protein 42 homolog {ECO:0000305} - 3.6.5.2 {ECO:0000269|PubMed:21565175, ECO:0000269|PubMed:23940119} - G25K GTP-binding protein |
|---|---|
| Gene names | CDC42 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | P60953 |
2
N-termini
2
C-termini
2
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MQTIKCVVVG DGAVGKTCLL ISYTTNKFPS EYVPTVFDNY AVTVMIGGEP YTLGLFDTAG
70 80 90 100 110 120
QEDYDRLRPL SYPQTDVFLV CFSVVSPSSF ENVKEKWVPE ITHHCPKTPF LLVGTQIDLR
130 140 150 160 170 180
DDPSTIEKLA KNKQKPITPE TAEKLARDLK AVKYVECSAL TQKGLKNVFD EAILAALEPP
190
EPKKSRRCVL L
Isoforms
- Isoform 1 of Cell division control protein 42 homologSequence View
10 20 30 40 50 60
MQTIKCVVVG DGAVGKTCLL ISYTTNKFPS EYVPTVFDNY AVTVMIGGEP YTLGLFDTAG
70 80 90 100 110 120
QEDYDRLRPL SYPQTDVFLV CFSVVSPSSF ENVKEKWVPE ITHHCPKTPF LLVGTQIDLR
130 140 150 160 170 180
DDPSTIEKLA KNKQKPITPE TAEKLARDLK AVKYVECSAL TQKGLKNVFD EAILAALEPP
190
EPKKSRRCVL L
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 2 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| P60953-1-unknown | MQTIKC... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| P60953-122-unknown | DPSTIE... | 122 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2875 | |||
| P60953-122-unknown | DPSTIE... | 122 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1961 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...IDLRDD | 121 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC2875 | |||
| ...IDLRDD | 121 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC1961 | |||
| ...KSRRCV | 188 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| CASP7_HUMAN | 121 | LRDD.|.DPST | inferred from experiment | unknown | MEROPS | Cerione RA | Tu S et al.:Cdc42 is a substrate for caspas... (C14.003) | 11278572, |
| CASP3_HUMAN | 121 | LRDD.|.DPST | inferred from experiment | unknown | MEROPS | Bokoch GM | Danley DE et al.:Defective Rho GTPase regulation... (C14.003) | 8752894, |
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|