P61202: COP9 signalosome complex subunit 2
Protein names | - COP9 signalosome complex subunit 2 - SGN2 - Signalosome subunit 2 - Alien homolog - JAB1-containing signalosome subunit 2 - Thyroid receptor-interacting protein 15 - TR-interacting protein 15 - TRIP-15 |
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Gene names | Cops2 |
Organism | Mus musculus |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P61202 |
2
N-termini
2
C-termini
1
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MSDMEDDFMC DDEEDYDLEY SEDSNSEPNV DLENQYYNSK ALKEDDPKAA LSSFQKVLEL
70 80 90 100 110 120
EGEKGEWGFK ALKQMIKINF KLTNFPEMMN RYKQLLTYIR SAVTRNYSEK SINSILDYIS
130 140 150 160 170 180
TSKQMDLLQE FYETTLEALK DAKNDRLWFK TNTKLGKLYL EREEYGKLQK ILRQLHQSCQ
190 200 210 220 230 240
TDDGEDDLKK GTQLLEIYAL EIQMYTAQKN NKKLKALYEQ SLHIKSAIPH PLIMGVIREC
250 260 270 280 290 300
GGKMHLREGE FEKAHTDFFE AFKNYDESGS PRRTTCLKYL VLANMLMKSG INPFDSQEAK
310 320 330 340 350 360
PYKNDPEILA MTNLVSAYQN NDITEFEKIL KTNHSNIMDD PFIREHIEEL LRNIRTQVLI
370 380 390 400 410 420
KLIKPYTRIH IPFISKELNI DVADVESLLV QCILDNTIHG RIDQVNQLLE LDHQKRGGAR
430 440
YTALDKWTNQ LNSLNQAVVS KLA
Isoforms
- Isoform 2 of COP9 signalosome complex subunit 2Sequence View
10 20 30 40 50 60
MSDMEDDFMC DDEEDYDLEY SEDSNSEPNV DLENQYYNSK ALKEDDPKAA LSSFQKVLEL
70 80 90 100 110 120
EGEKGEWGFK ALKQMIKINF KLTNFPEMMN RYKQLLTYIR SAVTRNYSEK SINSILDYIS
130 140 150 160 170 180
TSKQMDLLQE FYETTLEALK DAKNDRLWFK TNTKLGKLYL EREEYGKLQK ILRQLHQSCQ
190 200 210 220 230 240
TDDGEDDLKK GTQLLEIYAL EIQMYTAQKN NKKLKALYEQ SLHIKSAIPH PLIMGVIREC
250 260 270 280 290 300
GGKMHLREGE FEKAHTDFFE AFKNYDESGS PRRTTCLKYL VLANMLMKSG INPFDSQEAK
310 320 330 340 350 360
PYKNDPEILA MTNLVSAYQN NDITEFEKIL KTNHSNIMDD PFIREHIEEL LRNIRTQVLI
370 380 390 400 410 420
KLIKPYTRIH IPFISKELNI DVADVESLLV QCILDNTIHG RIDQVNQLLE LDHQKRGGAR
430 440
YTALDKWTNQ LNSLNQAVVS KLA
Protein Neighborhood
Domains & Features
2 N-termini - 2 C-termini - 1 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P61202-1-unknown | MSDMED... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
P61202-1-unknown | MSDMED... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt71908 | |||
P61202-259-unknown | FEAFKN... | 259 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30155 | |||
P61202-259-unknown | FEAFKN... | 259 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt149027 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...AHTDFF | 258 | inferred from cleavage | unknown | TopFIND | Inferred from cleavage TC30155 | |||
...AHTDFF | 258 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt132410 | |||
...VSKLA | 443 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...VSKLA | 443 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt67526 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
CATE_MOUSE | 258 | TDFF.|.FEAF | inferred from experiment | unknown | MEROPS | Merops CATE_MOUSE -> CSN2_MOUSE @258 |
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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