P62993: Growth factor receptor-bound protein 2

General Information

Protein names	- Growth factor receptor-bound protein 2 - Adapter protein GRB2 - Protein Ash - SH2/SH3 adapter GRB2
Gene names	GRB2
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	P62993

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK NYIEMKPHPW
        70         80         90        100        110        120
FFGKIPRAKA EEMLSKQRHD GAFLIRESES APGDFSLSVK FGNDVQHFKV LRDGAGKYFL
       130        140        150        160        170        180
WVVKFNSLNE LVDYHRSTSV SRNQQIFLRD IEQVPQQPTY VQALFDFDPQ EDGELGFRRG
       190        200        210
DFIHVMDNSD PNWWKGACHG QTGMFPRNYV TPVNRNV

Isoforms

- Isoform 2 of Growth factor receptor-bound protein 2

Sequence View

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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
P62993-1-Acetylation	MEAIAK...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
P62993-1-Acetylation	MEAIAK...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
P62993-1-Acetylation	MEAIAK...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
P62993-1-Acetylation	MEAIAK...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt96678
P62993-1-unknown	MEAIAK...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt76404

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...VNRNV	217	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...VNRNV	217	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt72022

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)