P62993: Growth factor receptor-bound protein 2
Protein names | - Growth factor receptor-bound protein 2 - Adapter protein GRB2 - Protein Ash - SH2/SH3 adapter GRB2 |
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Gene names | GRB2 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | P62993 |
2
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK NYIEMKPHPW
70 80 90 100 110 120
FFGKIPRAKA EEMLSKQRHD GAFLIRESES APGDFSLSVK FGNDVQHFKV LRDGAGKYFL
130 140 150 160 170 180
WVVKFNSLNE LVDYHRSTSV SRNQQIFLRD IEQVPQQPTY VQALFDFDPQ EDGELGFRRG
190 200 210
DFIHVMDNSD PNWWKGACHG QTGMFPRNYV TPVNRNV
Isoforms
- Isoform 2 of Growth factor receptor-bound protein 2Sequence View
10 20 30 40 50 60
MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK NYIEMKPHPW
70 80 90 100 110 120
FFGKIPRAKA EEMLSKQRHD GAFLIRESES APGDFSLSVK FGNDVQHFKV LRDGAGKYFL
130 140 150 160 170 180
WVVKFNSLNE LVDYHRSTSV SRNQQIFLRD IEQVPQQPTY VQALFDFDPQ EDGELGFRRG
190 200 210
DFIHVMDNSD PNWWKGACHG QTGMFPRNYV TPVNRNV
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
P62993-1-Acetylation | MEAIAK... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
P62993-1-Acetylation | MEAIAK... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: Complementary positional proteomics for screening substrates... | 20526345 | ||
P62993-1-Acetylation | MEAIAK... | 1 | acetylation- | COFRADIC | Gevaert K. | Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... | 20526345 | ||
P62993-1-Acetylation | MEAIAK... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt96678 | ||
P62993-1-unknown | MEAIAK... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt76404 |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
...VNRNV | 217 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
...VNRNV | 217 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt72022 |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
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