P63058: Thyroid hormone receptor alpha

General Information

Protein names	- Thyroid hormone receptor alpha - Nuclear receptor subfamily 1 group A member 1 - c-erbA-1 - c-erbA-alpha
Gene names	Thra
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	P63058

1 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform Alpha-1 of Thyroid hormone receptor alpha - Isoform Alpha-3 of Thyroid hormone receptor alpha - Isoform Alpha-deltaE6 of Thyroid hormone receptor alpha

Sequence View

        10         20         30         40         50         60
MEQKPSKVEC GSDPEENSAR SPDGKRKRKN GQCPLKSSMS GYIPSYLDKD EQCVVCGDKA
        70         80         90        100        110        120
TGYHYRCITC EGCKGFFRRT IQKNLHPTYS CKYDSCCVID KITRNQCQLC RFKKCIAVGM
       130        140        150        160        170        180
AMDLVLDDSK RVAKRKLIEQ NRERRRKEEM IRSLQQRPEP TPEEWDLIHV ATEAHRSTNA
       190        200        210        220        230        240
QGSHWKQRRK FLPDDIGQSP IVSMPDGDKV DLEAFSEFTK IITPAITRVV DFAKKLPMFS
       250        260        270        280        290        300
ELPCEDQIIL LKGCCMEIMS LRAAVRYDPE SDTLTLSGEM AVKREQLKNG GLGVVSDAIF
       310        320        330        340        350        360
ELGKSLSAFN LDDTEVALLQ AVLLMSTDRS GLLCVDKIEK SQEAYLLAFE HYVNHRKHNI
       370        380        390        400        410        420
PHFWPKLLMK EREVQSSILY KGAAAEGRPG GSLGVHPEGQ QLLGMHVVQG PQVRQLEQQL
       430        440        450        460        470        480
GEAGSLRGPV LQHQSPKSPQ QRLLELLHRS GILHSRAVCG EDDSSEASSL SSSSDTEDTE
       490
VCEDQAGKAA SP         10         20         30         40         50         60
MEQKPSKVEC GSDPEENSAR SPDGKRKRKN GQCPLKSSMS GYIPSYLDKD EQCVVCGDKA
        70         80         90        100        110        120
TGYHYRCITC EGCKGFFRRT IQKNLHPTYS CKYDSCCVID KITRNQCQLC RFKKCIAVGM
       130        140        150        160        170        180
AMDLVLDDSK RVAKRKLIEQ NRERRRKEEM IRSLQQRPEP TPEEWDLIHV ATEAHRSTNA
       190        200        210        220        230        240
QGSHWKQRRK FLPDDIGQSP IVSMPDGDKV DLEAFSEFTK IITPAITRVV DFAKKLPMFS
       250        260        270        280        290        300
ELPCEDQIIL LKGCCMEIMS LRAAVRYDPE SDTLTLSGEM AVKREQLKNG GLGVVSDAIF
       310        320        330        340        350        360
ELGKSLSAFN LDDTEVALLQ AVLLMSTDRS GLLCVDKIEK SQEAYLLAFE HYVNHRKHNI
       370        380        390        400        410        420
PHFWPKLLMK EREVQSSILY KGAAAEGRPG GSLGVHPEGQ QLLGMHVVQG PQVRQLEQQL
       430        440        450        460        470        480
GEAGSLRGPV LQHQSPKSPQ QRLLELLHRS GILHSRAVCG EDDSSEASSL SSSSDTEDTE
       490
VCEDQAGKAA SP         10         20         30         40         50         60
MEQKPSKVEC GSDPEENSAR SPDGKRKRKN GQCPLKSSMS GYIPSYLDKD EQCVVCGDKA
        70         80         90        100        110        120
TGYHYRCITC EGCKGFFRRT IQKNLHPTYS CKYDSCCVID KITRNQCQLC RFKKCIAVGM
       130        140        150        160        170        180
AMDLVLDDSK RVAKRKLIEQ NRERRRKEEM IRSLQQRPEP TPEEWDLIHV ATEAHRSTNA
       190        200        210        220        230        240
QGSHWKQRRK FLPDDIGQSP IVSMPDGDKV DLEAFSEFTK IITPAITRVV DFAKKLPMFS
       250        260        270        280        290        300
ELPCEDQIIL LKGCCMEIMS LRAAVRYDPE SDTLTLSGEM AVKREQLKNG GLGVVSDAIF
       310        320        330        340        350        360
ELGKSLSAFN LDDTEVALLQ AVLLMSTDRS GLLCVDKIEK SQEAYLLAFE HYVNHRKHNI
       370        380        390        400        410        420
PHFWPKLLMK EREVQSSILY KGAAAEGRPG GSLGVHPEGQ QLLGMHVVQG PQVRQLEQQL
       430        440        450        460        470        480
GEAGSLRGPV LQHQSPKSPQ QRLLELLHRS GILHSRAVCG EDDSSEASSL SSSSDTEDTE
       490
VCEDQAGKAA SP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
P63058-1-unknown	MEQKPS...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
P63058-1-unknown	MEQKPS...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92081
P63058-1-unknown	MEQKPS...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92082
P63058-1-unknown	MEQKPS...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92083

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ATGYHY	64	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000123056
...ATGYHY	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153956
...ATGYHY	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153957
...ATGYHY	64	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153958
...HRSGIL	452	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115323
...KAASP	492	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KAASP	492	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87700

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)