TopFIND 4.0

P70181: Phosphatidylinositol 4-phosphate 5-kinase type-1 beta

General Information

Protein names
- Phosphatidylinositol 4-phosphate 5-kinase type-1 beta
- PIP5K1-beta
- PtdIns(4)P-5-kinase 1 beta
- 2.7.1.68
- Phosphatidylinositol 4-phosphate 5-kinase type I alpha
- PIP5KIalpha
- Phosphatidylinositol 4-phosphate 5-kinase type I beta
- PIP5KIbeta
Gene names Pip5k1b
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P70181

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSSTAENGDA VPGKQNEEKT YKKTASSAIK GAIQLGIGYT VGNLTSKPER DVLMQDFYVV 
        70         80         90        100        110        120 
ESVFLPSEGS NLTPAHHYPD FRFKTYAPLA FRYFRELFGI KPDDYLYSIC SEPLIELSNP 
       130        140        150        160        170        180 
GASGSLFFLT SDDEFIIKTV QHKEAEFLQK LLPGYYMNLN QNPRTLLPKF YGLYCMQSGG 
       190        200        210        220        230        240 
INIRIVVMNN VLPRAMRMHL TYDLKGSTYK RRASRKEREK PNPTFKDLDF LQDMHEGLYF 
       250        260        270        280        290        300 
DTETYNALMK TLQRDCRVLE SFKIMDYSLL LGIHILDHSL KDKEEEPLQN VPDAKRPGMQ 
       310        320        330        340        350        360 
KVLYSTAMES IQGPGKSADG IIAENPDTMG GIPAKSHKGE KLLLFMGIID ILQSYRLMKK 
       370        380        390        400        410        420 
LEHSWKALVY DGDTVSVHRP SFYADRFLKF MNSRVFKKIQ ALKASPSKKR CNSIAALKAT 
       430        440        450        460        470        480 
SQEIVSSISQ EWKDEKRDLL TEGQSFSSLD EEALGSRHRP DLVPSTPSLF EAASLATTIS 
       490        500        510        520        530    
SSSLYVGEHY PHDRTTLYSN SKGLPSSSTF TLEEGTIYLT AEPNTLDLQD DASVLDVYL

Isoforms

- Isoform 2 of Phosphatidylinositol 4-phosphate 5-kinase type-1 beta

Sequence View

        10         20         30         40         50         60 
MSSTAENGDA VPGKQNEEKT YKKTASSAIK GAIQLGIGYT VGNLTSKPER DVLMQDFYVV 
        70         80         90        100        110        120 
ESVFLPSEGS NLTPAHHYPD FRFKTYAPLA FRYFRELFGI KPDDYLYSIC SEPLIELSNP 
       130        140        150        160        170        180 
GASGSLFFLT SDDEFIIKTV QHKEAEFLQK LLPGYYMNLN QNPRTLLPKF YGLYCMQSGG 
       190        200        210        220        230        240 
INIRIVVMNN VLPRAMRMHL TYDLKGSTYK RRASRKEREK PNPTFKDLDF LQDMHEGLYF 
       250        260        270        280        290        300 
DTETYNALMK TLQRDCRVLE SFKIMDYSLL LGIHILDHSL KDKEEEPLQN VPDAKRPGMQ 
       310        320        330        340        350        360 
KVLYSTAMES IQGPGKSADG IIAENPDTMG GIPAKSHKGE KLLLFMGIID ILQSYRLMKK 
       370        380        390        400        410        420 
LEHSWKALVY DGDTVSVHRP SFYADRFLKF MNSRVFKKIQ ALKASPSKKR CNSIAALKAT 
       430        440        450        460        470        480 
SQEIVSSISQ EWKDEKRDLL TEGQSFSSLD EEALGSRHRP DLVPSTPSLF EAASLATTIS 
       490        500        510        520        530    
SSSLYVGEHY PHDRTTLYSN SKGLPSSSTF TLEEGTIYLT AEPNTLDLQD DASVLDVYL



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P70181-1-unknown MSSTAE... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P70181-1-unknown MSSTAE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt85140

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LDVYL 539 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LDVYL 539 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt80758

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)