TopFIND 4.0

P70182: Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

General Information

Protein names
- Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
- PIP5K1-alpha
- PtdIns(4)P-5-kinase 1 alpha
- 2.7.1.68
- 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase
- Phosphatidylinositol 4-phosphate 5-kinase type I alpha
- PIP5KIalpha
- Phosphatidylinositol 4-phosphate 5-kinase type I beta
- PI4P5KIbeta
Gene names Pip5k1a
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P70182

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASASSGPAA AGFSSLDAGA PAGTAAASGI KRATVSEGPS ASVMPVKKIG HRSVDSSGET 
        70         80         90        100        110        120 
TYKKTTSSAL KGAIQLGITH TVGSLSTKPE RDVLMQDFYV VESIFFPSEG SNLTPAHHYN 
       130        140        150        160        170        180 
DFRFKTYAPV AFRYFRELFG IRPDDYLYSL CSEPLIELSN SGASGSLFYV SSDDEFIIKT 
       190        200        210        220        230        240 
VQHKEAEFLQ KLLPGYYMNL NQNPRTLLPK FYGLYCVQAG GKNIRIVVMN NLLPRSVKMH 
       250        260        270        280        290        300 
MKYDLKGSTY KRRASQKERE KTLPTFKDLD FLQDIPDGLF LDADMYSALC KTLQRDCLVL 
       310        320        330        340        350        360 
QSFKIMDYSL LMSIHNMDHA QREPTSNDTQ YSADTRRPAP QKALYSTAME SIQGEARRGG 
       370        380        390        400        410        420 
TVETEDHMGG IPARNNKGER LLLYIGIIDI LQSYRFVKKL EHSWKALVHD GDTVSVHRPG 
       430        440        450        460        470        480 
FYAERFQRFM CNTVFKKIPL KPSPTKKFRS GPSFSRRSGP SGNSCTSQLM ASGEHRAQVT 
       490        500        510        520        530        540 
TKAEVEPDVH LGRPDVLPQT PPLEEISEGS PVPGPSFSPV VGQPLQILNL SSTLEKLDVA 
   
ESEFTH

Isoforms

- Isoform 2 of Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha - Isoform 3 of Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

Sequence View

        10         20         30         40         50         60 
MASASSGPAA AGFSSLDAGA PAGTAAASGI KRATVSEGPS ASVMPVKKIG HRSVDSSGET 
        70         80         90        100        110        120 
TYKKTTSSAL KGAIQLGITH TVGSLSTKPE RDVLMQDFYV VESIFFPSEG SNLTPAHHYN 
       130        140        150        160        170        180 
DFRFKTYAPV AFRYFRELFG IRPDDYLYSL CSEPLIELSN SGASGSLFYV SSDDEFIIKT 
       190        200        210        220        230        240 
VQHKEAEFLQ KLLPGYYMNL NQNPRTLLPK FYGLYCVQAG GKNIRIVVMN NLLPRSVKMH 
       250        260        270        280        290        300 
MKYDLKGSTY KRRASQKERE KTLPTFKDLD FLQDIPDGLF LDADMYSALC KTLQRDCLVL 
       310        320        330        340        350        360 
QSFKIMDYSL LMSIHNMDHA QREPTSNDTQ YSADTRRPAP QKALYSTAME SIQGEARRGG 
       370        380        390        400        410        420 
TVETEDHMGG IPARNNKGER LLLYIGIIDI LQSYRFVKKL EHSWKALVHD GDTVSVHRPG 
       430        440        450        460        470        480 
FYAERFQRFM CNTVFKKIPL KPSPTKKFRS GPSFSRRSGP SGNSCTSQLM ASGEHRAQVT 
       490        500        510        520        530        540 
TKAEVEPDVH LGRPDVLPQT PPLEEISEGS PVPGPSFSPV VGQPLQILNL SSTLEKLDVA 
   
ESEFTH         10         20         30         40         50         60 
MASASSGPAA AGFSSLDAGA PAGTAAASGI KRATVSEGPS ASVMPVKKIG HRSVDSSGET 
        70         80         90        100        110        120 
TYKKTTSSAL KGAIQLGITH TVGSLSTKPE RDVLMQDFYV VESIFFPSEG SNLTPAHHYN 
       130        140        150        160        170        180 
DFRFKTYAPV AFRYFRELFG IRPDDYLYSL CSEPLIELSN SGASGSLFYV SSDDEFIIKT 
       190        200        210        220        230        240 
VQHKEAEFLQ KLLPGYYMNL NQNPRTLLPK FYGLYCVQAG GKNIRIVVMN NLLPRSVKMH 
       250        260        270        280        290        300 
MKYDLKGSTY KRRASQKERE KTLPTFKDLD FLQDIPDGLF LDADMYSALC KTLQRDCLVL 
       310        320        330        340        350        360 
QSFKIMDYSL LMSIHNMDHA QREPTSNDTQ YSADTRRPAP QKALYSTAME SIQGEARRGG 
       370        380        390        400        410        420 
TVETEDHMGG IPARNNKGER LLLYIGIIDI LQSYRFVKKL EHSWKALVHD GDTVSVHRPG 
       430        440        450        460        470        480 
FYAERFQRFM CNTVFKKIPL KPSPTKKFRS GPSFSRRSGP SGNSCTSQLM ASGEHRAQVT 
       490        500        510        520        530        540 
TKAEVEPDVH LGRPDVLPQT PPLEEISEGS PVPGPSFSPV VGQPLQILNL SSTLEKLDVA 
   
ESEFTH



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P70182-1-unknown MASASS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    P70182-1-unknown MASASS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt85136
    P70182-1-unknown MASASS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt85137

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)