TopFIND 4.0

P70453: High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A

General Information

Protein names
- High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
- 3.1.4.53
- P2A
Gene names Pde7a
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P70453

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGITLIWCLA LVLIKWITSK RRGAISYDSS DQTALYIRML GDVRVRSRAG FETERRGSHP 
        70         80         90        100        110        120 
YIDFRIFHSQ SDIEASVSAR NIRRLLSFQR YLRSSRVFRG ATVCSSLDIL DEDYNGQAKC 
       130        140        150        160        170        180 
MLEKVGNWNF DIFLFDRLTN GNSLVSLTFH LFSLHGLIEY FHLDMVKLRR FLVMIQEDYH 
       190        200        210        220        230        240 
SQNPYHNAVH AADVTQAMHC YLKEPKLASS VTPWDILLSL IAAATHDLDH PGVNQPFLIK 
       250        260        270        280        290        300 
TNHYLATLYK NSSVLENHHW RSAVGLLRES GLFSHLPLES RQEMEAQIGA LILATDISRQ 
       310        320        330        340        350        360 
NEYLSLFRSH LDKGDLHLDD GRHRHLVLQM ALKCADICNP CRNWELSKQW SEKVTEEFFH 
       370        380        390        400        410        420 
QGDIEKKYHL GVSPLCDRQT ESIANIQIGF MTYLVEPLFT EWARFSDTRL SQTMLGHVGL 
       430        440        450    
NKASWKGLQR QQPSSEDANA AFELNSQLLT QENRLS

Isoforms

- Isoform 2 of High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A

Sequence View

        10         20         30         40         50         60 
MGITLIWCLA LVLIKWITSK RRGAISYDSS DQTALYIRML GDVRVRSRAG FETERRGSHP 
        70         80         90        100        110        120 
YIDFRIFHSQ SDIEASVSAR NIRRLLSFQR YLRSSRVFRG ATVCSSLDIL DEDYNGQAKC 
       130        140        150        160        170        180 
MLEKVGNWNF DIFLFDRLTN GNSLVSLTFH LFSLHGLIEY FHLDMVKLRR FLVMIQEDYH 
       190        200        210        220        230        240 
SQNPYHNAVH AADVTQAMHC YLKEPKLASS VTPWDILLSL IAAATHDLDH PGVNQPFLIK 
       250        260        270        280        290        300 
TNHYLATLYK NSSVLENHHW RSAVGLLRES GLFSHLPLES RQEMEAQIGA LILATDISRQ 
       310        320        330        340        350        360 
NEYLSLFRSH LDKGDLHLDD GRHRHLVLQM ALKCADICNP CRNWELSKQW SEKVTEEFFH 
       370        380        390        400        410        420 
QGDIEKKYHL GVSPLCDRQT ESIANIQIGF MTYLVEPLFT EWARFSDTRL SQTMLGHVGL 
       430        440        450    
NKASWKGLQR QQPSSEDANA AFELNSQLLT QENRLS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P70453-1-unknown MGITLI... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ENRLS 456 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...ENRLS 456 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt80324

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)