TopFIND 4.0

P70658: C-X-C chemokine receptor type 4

General Information

Protein names
- C-X-C chemokine receptor type 4
- CXC-R4
- CXCR-4
- Fusin {ECO:0000303|PubMed:8955194}
- Leukocyte-derived seven transmembrane domain receptor
- LESTR {ECO:0000303|PubMed:9295051}
- Pre-B-cell-derived chemokine receptor
- PB-CKR
- Stromal cell-derived factor 1 receptor
- SDF-1 receptor
- CD184
Gene names Cxcr4
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID P70658

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEPISVSIYT SDNYSEEVGS GDYDSNKEPC FRDENVHFNR IFLPTIYFII FLTGIVGNGL 
        70         80         90        100        110        120 
VILVMGYQKK LRSMTDKYRL HLSVADLLFV ITLPFWAVDA MADWYFGKFL CKAVHIIYTV 
       130        140        150        160        170        180 
NLYSSVLILA FISLDRYLAI VHATNSQRPR KLLAEKAVYV GVWIPALLLT IPDFIFADVS 
       190        200        210        220        230        240 
QGDISQGDDR YICDRLYPDS LWMVVFQFQH IMVGLILPGI VILSCYCIII SKLSHSKGHQ 
       250        260        270        280        290        300 
KRKALKTTVI LILAFFACWL PYYVGISIDS FILLGVIKQG CDFESIVHKW ISITEALAFF 
       310        320        330        340        350    
HCCLNPILYA FLGAKFKSSA QHALNSMSRG SSLKILSKGK RGGHSSVSTE SESSSFHSS

Isoforms

- Isoform CXCR4-A of C-X-C chemokine receptor type 4

Sequence View

        10         20         30         40         50         60 
MEPISVSIYT SDNYSEEVGS GDYDSNKEPC FRDENVHFNR IFLPTIYFII FLTGIVGNGL 
        70         80         90        100        110        120 
VILVMGYQKK LRSMTDKYRL HLSVADLLFV ITLPFWAVDA MADWYFGKFL CKAVHIIYTV 
       130        140        150        160        170        180 
NLYSSVLILA FISLDRYLAI VHATNSQRPR KLLAEKAVYV GVWIPALLLT IPDFIFADVS 
       190        200        210        220        230        240 
QGDISQGDDR YICDRLYPDS LWMVVFQFQH IMVGLILPGI VILSCYCIII SKLSHSKGHQ 
       250        260        270        280        290        300 
KRKALKTTVI LILAFFACWL PYYVGISIDS FILLGVIKQG CDFESIVHKW ISITEALAFF 
       310        320        330        340        350    
HCCLNPILYA FLGAKFKSSA QHALNSMSRG SSLKILSKGK RGGHSSVSTE SESSSFHSS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P70658-1-unknown MEPISV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)