TopFIND 4.0

P75960: NAD-dependent protein deacylase {ECO:0000255|HAMAP-Rule:MF_01121}

General Information

Protein names
- NAD-dependent protein deacylase {ECO:0000255|HAMAP-Rule:MF_01121}
- 3.5.1.- {ECO:0000255|HAMAP-Rule:MF_01121}
- Regulatory protein SIR2 homolog {ECO:0000255|HAMAP-Rule:MF_01121}
Gene names cobB
Organism Escherichia coli
Protease Family
Protease ID
Chromosome location
UniProt ID P75960

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLSRRGHRLS RFRKNKRRLR ERLRQRIFFR DKVVPEAMEK PRVLVLTGAG ISAESGIRTF 
        70         80         90        100        110        120 
RAADGLWEEH RVEDVATPEG FDRDPELVQA FYNARRRQLQ QPEIQPNAAH LALAKLQDAL 
       130        140        150        160        170        180 
GDRFLLVTQN IDNLHERAGN TNVIHMHGEL LKVRCSQSGQ VLDWTGDVTP EDKCHCCQFP 
       190        200        210        220        230        240 
APLRPHVVWF GEMPLGMDEI YMALSMADIF IAIGTSGHVY PAAGFVHEAK LHGAHTVELN 
       250        260        270    
LEPSQVGNEF AEKYYGPASQ VVPEFVEKLL KGLKAGSIA

Isoforms

- Isoform CobB-Short of NAD-dependent protein deacylase

Sequence View

        10         20         30         40         50         60 
MLSRRGHRLS RFRKNKRRLR ERLRQRIFFR DKVVPEAMEK PRVLVLTGAG ISAESGIRTF 
        70         80         90        100        110        120 
RAADGLWEEH RVEDVATPEG FDRDPELVQA FYNARRRQLQ QPEIQPNAAH LALAKLQDAL 
       130        140        150        160        170        180 
GDRFLLVTQN IDNLHERAGN TNVIHMHGEL LKVRCSQSGQ VLDWTGDVTP EDKCHCCQFP 
       190        200        210        220        230        240 
APLRPHVVWF GEMPLGMDEI YMALSMADIF IAIGTSGHVY PAAGFVHEAK LHGAHTVELN 
       250        260        270    
LEPSQVGNEF AEKYYGPASQ VVPEFVEKLL KGLKAGSIA



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    P75960-1-unknown MLSRRG... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...ELNLEP 242 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)